2.1.1.197: malonyl-[acyl-carrier protein] O-methyltransferase

This is an abbreviated version!
For detailed information about malonyl-[acyl-carrier protein] O-methyltransferase, go to the full flat file.

Reaction

malonyl-[acyl-carrier protein] methyl ester

Synonyms

BioC, S-adenosyl-L-methionine-dependent methyltransferase, SAM-dependent methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.197 malonyl-[acyl-carrier protein] O-methyltransferase

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Results	in table
10145	AA Sequence
2	Cloned(Commentary)
1	Cofactor
1	Expression
5	General Information
3	Inhibitors
2	kcat/KM [mM/s]
2	KM Value [mM]
1	Metals/Ions
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
8	Organism
3	Pathway
1	pH Optimum
1	pH Range
1	pI Value
4	Protein Variants
1	Purification (Commentary)
1	Reaction
7	Reference
10	Substrates and Products (Substrate)
1	Subunits
4	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

Reference

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Reference on EC 2.1.1.197 - malonyl-[acyl-carrier protein] O-methyltransferase

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1345

Wu, C.H.; Bao, Y.Y.; Shao, C.P.; Shiuan, D.

Molecular cloning and nucleotide sequencing of bioF (7-keto-8-amino pelargonic acid synthetase), bioC and bioD (dethiobiotin synthetase) genes of Erwinia herbicola

Biochem. Mol. Biol. Int.

311-315

1997

Pantoea agglomerans

9063571

487049

Otsuka, A.J.; Buoncristiani, M.R.; Howard, P.K.; Flamm, J.; Johnson, C.; Yamamoto, R.; Uchida, K.; Cook, C.; Ruppert, J.; Matsuzaki, J.

The Escherichia coli biotin biosynthetic enzyme sequences predicted from the nucleotide sequence of the bio operon

J. Biol. Chem.

263

19577-19585

1988

Escherichia coli (P12999)

3058702

708906

Cleary, P.P.; Campbell, A.

Deletion and complementation analysis of biotin gene cluster of Escherichia coli

J. Bacteriol.

112

830-839

1972

Escherichia coli

4563978

708943

Del Campillo-Campbell, A.; Kayajanian, G.; Campbell, A.; Adhya, S.

Biotin-requiring mutants of Escherichia coli K-12

J. Bacteriol.

2065-2066

1967

Escherichia coli K-12

4864413

710038

Lin, S.; Hanson, R.E.; Cronan, J.E.

Biotin synthesis begins by hijacking the fatty acid synthetic pathway

Nat. Chem. Biol.

682-688

2010

Escherichia coli

20693992

722785

Lin, S.; Cronan, J.E.

The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis

J. Biol. Chem.

287

37010-37020

2012

Bacillus cereus (Q731I1), Bacillus cereus ATCC 10987 (Q731I1)

22965231