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2.1.1.198: 16S rRNA (cytidine1402-2'-O)-methyltransferase

This is an abbreviated version!
For detailed information about 16S rRNA (cytidine1402-2'-O)-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
cytidine1402 in 16S rRNA
=
S-adenosyl-L-homocysteine
+
2'-O-methylcytidine1402 in 16S rRNA

Synonyms

RsmI, YraL

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.198 16S rRNA (cytidine1402-2'-O)-methyltransferase

General Information

General Information on EC 2.1.1.198 - 16S rRNA (cytidine1402-2'-O)-methyltransferase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
physiological function
both the 2'-O-methylation (catalyzed by RsmI) and N4-methylation of C1402 (catalyzed by RsmH) are needed for efficient initiation at the UUG and GUG codon. m4Cm1402 in the 16S rRNA modulates the accuracy of P-site function. The modification is needed for efficient translation initiation at the UUG and GUG codons