2.1.1.2: guanidinoacetate N-methyltransferase
This is an abbreviated version!
For detailed information about guanidinoacetate N-methyltransferase, go to the full flat file.
Reaction
Synonyms
GA methylpherase, GAA methyltransferase, GAMT, guanidinoacetate methyltransferase, guanidinoacetate N-methyltransferase, guanidinoacetate transmethylase, guanidoacetate methyltransferase, methionine-guanidinoacetic transmethylase, MIM 601240, N-guanidinoacetate methyltransferase, S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase
ECTree
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Inhibitors
Inhibitors on EC 2.1.1.2 - guanidinoacetate N-methyltransferase
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additional information
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complete and irreversible inactivation by ultraviolet irradiation
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oxidized form, S-adenosylmethionine protects against inactivation
glutathione
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readily reactivated by reduced glutathione, substrates do not protect against inactivation, guanidinoacetate together with sinefungin protects against inactivation, can be reactivated with thiol compounds
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complete inhibition at 1 mM, reversible by addition of glutathione
p-chloromercuribenzoate
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complete inhibition at 1 mM, reversible by addition of glutathione
p-chloromercuribenzoate
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complete inhibition at 1 mM, reversible by addition of glutathione
p-chloromercuribenzoate
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complete inhibition at 1 mM, reversible by addition of glutathione