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2.1.1.213: tRNA (guanine10-N2)-dimethyltransferase

This is an abbreviated version!
For detailed information about tRNA (guanine10-N2)-dimethyltransferase, go to the full flat file.

Word Map on EC 2.1.1.213

Reaction

2 S-adenosyl-L-methionine +

guanine10 in tRNA
= 2 S-adenosyl-L-homocysteine +
N2-dimethylguanine10 in tRNA

Synonyms

EC 2.1.1.32, N(2),N(2)-dimethylguanosine tRNA methyltransferase, PAB1283, PabTrm-G10, PabTrm-m2 2G10 enzyme, Trm-G10, tRNA:m2(2)G10 methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.213 tRNA (guanine10-N2)-dimethyltransferase

Substrates Products

Substrates Products on EC 2.1.1.213 - tRNA (guanine10-N2)-dimethyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2 S-adenosyl-L-methionine + guanine10 in tRNA
2 S-adenosyl-L-homocysteine + N2-dimethylguanine10 in tRNA
show the reaction diagram
S-adenosyl-L-methionine + guanine10 in tRNA
S-adenosyl-L-homocysteine + N2-methylguanine10 in tRNA
show the reaction diagram
additional information
?
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model for a potential binding mode for the THUMP domain, which may be common to various RNA modification enzymes that specifically modify nucleotides in the 3D-core of the tRNA molecule
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