2.1.1.220: tRNA (adenine58-N1)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (adenine58-N1)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.220

2.1.1.220

trnaimet

1-methyladenosine

nucleoside

mtases

two-subunit

thermus

exosome

polyadenylation

adomet

t-loop

polya

s-adenosylmethionine

n1-methylation

heterotetramer

homotetrameric

methionyl-trna

high-copy-number

eubacteria

methyltransferases

s-adenosyl-l-homocysteine

two-component

s-adenosyl-l-methionine-dependent

l-shaped

tpsic

trna-binding

hypomodified

drug development

Reaction

Synonyms

EC 2.1.1.36, Gcd10p, Gcd10p-Gcd14p, Gcd10pyGcd14p complex, Gcd14p, m1A58 MTase, m1A58 tRNA methyl-transferase, m1A58 tRNA methyltransferase, m1A58-methyltransferase, m1A58MTase, Rv2118c, Rv2118p, Trm6, TRM6-TRM61 holoenzyme, Trm61A, Trm61B, TRm61p, TRm6p, TrmI, tRNA (m1A58) methyltransferase, tRNA (m1A58) MTase, tRNA m(1)A58 methyltransferase, tRNA m1A58 methyltransferase, two component m1A58 tRNA methyl-transferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.220 tRNA (adenine58-N1)-methyltransferase

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Results	in table
10024	AA Sequence
1	Application
8	Cloned(Commentary)
17	Cofactor
15	Crystallization (Commentary)
9	Disease/ Diagnostics
51	General Information
2	Inhibitors
5	KM Value [mM]
6	Localization
6	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
32	Organism
1	Pathway
15	PDB ID
6	pH Optimum
11	Protein Variants
8	Purification (Commentary)
4	Reaction
30	Reference
6	Source Tissue
45	Substrates and Products (Substrate)
31	Subunits
74	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]

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Cloned on EC 2.1.1.220 - tRNA (adenine58-N1)-methyltransferase

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Saccharomyces cerevisiae

P46959; P41814

713140

coexpression of catalytic subunit Trm61p and non-catalytic subunit Trm6p in Saccharomyces cerevisiae

Homo sapiens

Q96FX7; Q9UJA5

713498

expression in Escherichia coli

2 entries

gene aq_311, recombinant expression in Escherichia coli strain Rosetta (DE3)

Aquifex aeolicus

O66653

736707

genes GCD10 and GCD14 encoding TRM6 and TRM61, expression of His-tagged proteins in Escherichia coli strain Rosetta (DE3)

Saccharomyces cerevisiae

718504

genes GCD10 and GCD14, recombinant co-expression of wild-type and selenomethionine-labeled His-tagged subunits in Escherichia coli

Saccharomyces cerevisiae

P41814; P46959

758373

recombinant expression of C-terminally His-tagged enzyme in Escherichia coli strain BL21(DE3)

Homo sapiens

Q96FX7

736642