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2.1.1.223: tRNA1Val (adenine37-N6)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA1Val (adenine37-N6)-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
adenine37 in tRNA1Val
=
S-adenosyl-L-homocysteine
+
N6-methyladenine37 in tRNA1Val

Synonyms

YfiC

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.223 tRNA1Val (adenine37-N6)-methyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.1.1.223 - tRNA1Val (adenine37-N6)-methyltransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + adenine37 in tRNA1(Val)
S-adenosyl-L-homocysteine + N6-methyladenine37 in tRNA1(Val)
show the reaction diagram
modification of adenine37 in the anticodon loop. The methylation of m6A in tRNA1 Val by YfiC has little influence on the cell growth under standard conditions, the yfiC gene confers a growth advantage under conditions of osmotic and oxidative stress
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