2.1.1.228: tRNA (guanine37-N1)-methyltransferase
This is an abbreviated version!
For detailed information about tRNA (guanine37-N1)-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.228
-
2.1.1.228
-
methyltransferases
-
anticodon
-
adomet
-
1-methylguanosine
-
drug development
-
n2-guanine
-
trmt10a
-
1-methyladenine
-
adomet-dependent
-
5-methyluridine
-
trmfo
-
n1-methylation
-
methyl-deficient
-
7-methylguanine
-
spout
-
epitranscriptome
-
nsun2-mediated
-
medicine
- 2.1.1.228
- methyltransferases
-
anticodon
- adomet
- 1-methylguanosine
- drug development
-
n2-guanine
- trmt10a
- 1-methyladenine
-
adomet-dependent
- 5-methyluridine
- trmfo
-
n1-methylation
-
methyl-deficient
- 7-methylguanine
-
spout
-
epitranscriptome
-
nsun2-mediated
- medicine
Reaction
Synonyms
At3g56120, aTrm5a methyltransferase, aTrm5a/Taw22-like enzyme, AtTrm5a, bacterial tRNA (guanine37-N1)-methyltransferase, bacterial tRNA-(N1G37) methyltransferase, EC 2.1.1.31, EcTrmD, HiTrmD, HsTrm5, m1G37 tRNA methyltransferase, m1G37-forming tRNA methyltransferase, Mj-Trm5, MJ0883, MjTrm5, MjTrm5b, mono-functional methyltransferase, More, MtbTrmD, NEQ228, PA14_15990, PAB2272, PAB_RS03940, PaTrm5a, PaTrm5b, PaTrmD, SaTrmD, Ta0997, TAW22, transfer RNA (m1G37) methyltransferase, Trm1, TRM5, Trm5a, Trm5a/Taw22-like enzyme, trm5b, Trm5p, TrmD, TRMT5, tRNA (guanine(37)-N1)-methyltransferase 1, tRNA (guanine37-N1)-methyltransferase, tRNA (guanosine-1) methyltransferase, tRNA (m1G37) methyltransferase, tRNA (m1G37)-methyltransferase, tRNA m1G37 methyltransferase, tRNA methyltransferase, tRNA methyltransferase 5, tRNA methyltransferase D, tRNA(m(1)G37)methyltransferase, tRNA(m1G37) methyltransferase, tRNA(m1G37) MTase, tRNA(m1G37)methyltransferase, tRNA-(N1G37) methyltransferase, tRNAPhe:imG2 methyltransferase
ECTree
2.1.1.228 tRNA (guanine37-N1)-methyltransferaseAdvanced search results
results (
results (Turnover Number
Turnover Number on EC 2.1.1.228 - tRNA (guanine37-N1)-methyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
TURNOVER NUMBER [1/s] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.01
guanine37 in Methanocaldococcus jannaschii tRNA(Cys)
pH 8.0, 50°C
-
0.078
guanine37 in tRNAArg
-
pH 8.0, temperature not specified in the publication
-
0.36
guanine37 in tRNAGlnG36A, guanine37 in tRNAGlnG36C
-
pH 8.0, temperature not specified in the publication
-
0.17
guanine37 in tRNAGlnG36U
-
pH 8.0, temperature not specified in the publication
-
0.0113
guanine37 in tRNALeu(CAG)
pH and temperature not specified in the publication
-
0.217
guanine37 in tRNALeu(GAG)
pH 7.5, 37°C, recombinant enzyme
-
0.13
guanine37 in tRNAPro
-
pH 8.0, temperature not specified in the publication
-
0.0001
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, mutant enzyme P267A
-
0.0003
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, mutant enzyme D223A
-
0.0013
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, mutant enzyme N265A
-
0.0013
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, mutant enzyme Y176A
-
0.0015
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, mutant enzyme G205A/G207A
-
0.0018
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, mutant enzyme P226A
-
0.003
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, mutant enzyme R144A
-
0.0037
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, mutant enzyme N225A
-
0.0083
guanine37 in Methanocaldococcus jannaschii tRNACys
pH 8.0, 50°C, wild-type enzyme
-
0.0086
guanine37 in Methanocaldococcus jannaschii tRNAPro
pH 8.0, 52°C
-
0.0014
guanine37 in tRNAGlnCUG
-
pH 8.0, temperature not specified in the publication
-
0.0047
guanine37 in tRNAGlnCUG
-
pH 8.0, temperature not specified in the publication
-
0.24
guanine37 in tRNAGlnCUG
-
pH 8.0, temperature not specified in the publication
-
0.34
guanine37 in tRNAGlnCUG
-
pH 8.0, temperature not specified in the publication
-
0.049
guanine37 in tRNALeu
recombinant wild-type enzyme, pH 8.0, 30°C
-
0.093
guanine37 in tRNALeu
recombinant wild-type enzyme, pH 8.0, 37°C
-
0.13
guanine37 in tRNALeu
recombinant wild-type enzyme, pH 8.0, 43°C
-
0.32
guanine37 in tRNALeu
-
pH 8.0, temperature not specified in the publication
-
0.0001
S-adenosyl-L-methionine
pH 8.0, 50°C, mutant enzyme P267A
0.0105
S-adenosyl-L-methionine
pH and temperature not specified in the publication
0.012
S-adenosyl-L-methionine
pH 8.0, 50°C, wild-type enzyme
0.02
S-adenosyl-L-methionine
-
kcat in steady-state phase turnover, pH and temperature not specified in the publication
0.09
S-adenosyl-L-methionine
-
pH and temperature not specified in the publication
additional information
additional information
-
kinetic analysis of tRNA truncation mutants and tRNA mutant with alterations in the anticodon loop reveals that TrmD and Trm5 exhibit separate and distinct mode of tRNA recognition, suggesting that they evolved by independent and nonoverlapping pathways from their unrelated AdoMet families
-
additional information
additional information
kinetic analysis of tRNA truncation mutants and tRNA mutant with alterations in the anticodon loop reveals that TrmD and Trm5 exhibit separate and distinct mode of tRNA recognition, suggesting that they evolved by independent and nonoverlapping pathways from their unrelated AdoMet families
-
additional information
additional information
-
0.12 is kchem in the first rapid burst turnover
-
