2.1.1.245: 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase

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For detailed information about 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.245

2.1.1.245

methanogen

metr

methanosarcina

clostridium

thermoaceticum

ch3-h4folate

n5-methyl

pka

cobalt

ragsdale

acetyl-enzyme

h4folate

barkeri

thermophila

ni

cfesp

exafs

unprotonated

pre-steady-state

methane

xanes

cobiamide

stopped-flow

multienzyme

shoemaker

tetrahedral

electrophilic

companion

cobalamin-dependent

a-cluster

organometallic

h2o

Reaction

a [methyl-Co(III) corrinoid Fe-S protein]

Synonyms

AcdS, acetyl-CoA decarbonylase/synthase complex, C/Fe-S enzyme, cdhD, CdhD1, cdhE, CH3-H4pteridine:cob(I)amide-protein methyltransferase, methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase, MeTr

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.245 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase

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Results	in table
617	AA Sequence
1	Cloned(Commentary)
4	General Information
2	Inhibitors
3	KM Value [mM]
3	Metals/Ions
2	Natural Substrates/ Products (Substrates)
5	Organism
1	Pathway
3	pH Optimum
2	Purification (Commentary)
2	Reaction
5	Reference
7	Substrates and Products (Substrate)
1	Subunits
11	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.1.1.245 - 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase

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5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein methyltransferase

Catalyses the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin. Forms, together with EC 1.2.7.4, anaerobic carbon-monoxide dehydrogenase, and EC 2.3.1.169, CO-methylating acetyl-CoA synthase, the acetyl-CoA decarbonylase/synthase complex that catalyses the demethylation of acetyl-CoA in a reaction that also forms CO2. This reaction is a key step in methanogenesis from acetate.