2.1.1.249: dimethylamine-corrinoid protein Co-methyltransferase

This is an abbreviated version!
For detailed information about dimethylamine-corrinoid protein Co-methyltransferase, go to the full flat file.

Reaction

Synonyms

dimethyl-12-HBI methyltransferase, dimethylamine methyltransferase, dimethylamine/5-hydroxybenzimidazolylcobamide methyltransferase, dimethylamine: corrinoid methyltransferase, dimethylamine:CoM methyltransferase, dimethylamine:corrinoid methyltransferase, DMA methyltransferase, DMA-MT, DMA:CoM methyltransferase, DMA:corrinoid methyltransferase, MtbB, MtbB1, MtbB2, MtbB3, MtcB

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.249 dimethylamine-corrinoid protein Co-methyltransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
7	Activating Compound
277	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
2	Cofactor
16	General Information
2	Inhibitors
1	Ki Value [mM]
3	Metals/Ions
8	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
27	Organism
3	Pathway
3	pH Optimum
1	pI Value
5	Purification (Commentary)
3	Reaction
15	Reference
2	Source Tissue
2	Specific Activity [micromol/min/mg]
22	Substrates and Products (Substrate)
8	Subunits
34	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 2.1.1.249 - dimethylamine-corrinoid protein Co-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

dimethylamine:5-hydroxybenzimidazolylcobamide Co-methyltransferase

The enzyme, which catalyses the transfer of a methyl group from dimethylamine to a dimethylamine-specific corrinoid protein (MtbC), is involved in methanogenesis from dimethylamine. The enzyme contains the unusual amino acid pyrrolysine [3]. Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state. During methylation the cobalt is oxidized to the Co(III) state. The methylated corrinoid protein is substrate for EC 2.1.1.247, methylated methylamine-specific corrinoid protein:coenzyme M methyltransferase.