2.1.1.292: carminomycin 4-O-methyltransferase
This is an abbreviated version!
For detailed information about carminomycin 4-O-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.292
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2.1.1.292
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methyltransferases
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sam-dependent
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s-adenosyl-l-homocysteine
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daunorubicin
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peucetius
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s-adenosyl-l-methionine-dependent
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synthesis
- 2.1.1.292
- methyltransferases
-
sam-dependent
- s-adenosyl-l-homocysteine
- daunorubicin
- peucetius
-
s-adenosyl-l-methionine-dependent
- synthesis
Reaction
Synonyms
4-O-methyltransferase, anthracycline 4-O-methyltransferase, anthracycline methyltransferase, carminomycin 4-OMT, class I methyltransferase, COMT, DauK, DnrK
ECTree
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Crystallization
Crystallization on EC 2.1.1.292 - carminomycin 4-O-methyltransferase
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purified enzyme mutant DnrK-Ser in complex with aclacinomycin T and S-adenosyl-L-homocysteine, X-ray diffraction structure determination and analysis at 1.9 A resolution
the crystal structure of the ternary complex of this enzyme with the bound products S-adenosyl-L-homocysteine and 4-methoxy-epsilon-rhodomycin T is determined to a 2.35 A resolution, vapor diffusion method at 20°C