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2.1.1.3: thetin-homocysteine S-methyltransferase

This is an abbreviated version!
For detailed information about thetin-homocysteine S-methyltransferase, go to the full flat file.

Reaction

dimethylsulfonioacetate
+
L-homocysteine
=
(methylsulfanyl)acetate
+
L-methionine

Synonyms

dimethylthetin-homocysteine methyltransferase, methyltransferase, dimethylthetin-homocysteine, More, thetin-homocysteine methylpherase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.3 thetin-homocysteine S-methyltransferase

Inhibitors

Inhibitors on EC 2.1.1.3 - thetin-homocysteine S-methyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cu2+
-
0.01 M, strong
glycine betaine
-
0.1 M
Hg2+
-
0.01 M, strong
hydroxylamine
-
0.01 M
phenylhydrazine
-
0.01 M
Sodium mercaptoacetate
-
-
Zn2+
-
0.01 M, strong
additional information
-
no inhibition by dimethylthetin, sulfocholine (up to 0.1 M), mercaptoethanol, cysteine, Na2SO4, Li+, Cs+, Ca2+, Mg2+, NaN3, NaCN, NaF, EDTA, semicarbazide, iodoacetate
-