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2.1.1.309: 18S rRNA (guanine1575-N7)-methyltransferase

This is an abbreviated version!
For detailed information about 18S rRNA (guanine1575-N7)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.309

Reaction

S-adenosyl-L-methionine
+
guanine1575 in 18S rRNA
=
S-adenosyl-L-homocysteine
+
N7-methylguanine1575 in 18S rRNA

Synonyms

18S rRNA methyltransferase, BUD23, rRNA methyltransferase Bud23, WBSCR22, WBSCR22-TRMT112

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.309 18S rRNA (guanine1575-N7)-methyltransferase

Reference

Reference on EC 2.1.1.309 - 18S rRNA (guanine1575-N7)-methyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
White, J.; Li, Z.; Sardana, R.; Bujnicki, J.M.; Marcotte, E.M.; Johnson, A.W.
Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits
Mol. Cell. Biol.
28
3151-3161
2008
Saccharomyces cerevisiae (P25627), Saccharomyces cerevisiae
Manually annotated by BRENDA team
Figaro, S.; Wacheul, L.; Schillewaert, S.; Graille, M.; Huvelle, E.; Mongeard, R.; Zorbas, C.; Lafontaine, D.L.; Heurgue-Hamard, V.
Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575
Mol. Cell. Biol.
32
2254-2267
2012
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Zorbas, C.; Nicolas, E.; Wacheul, L.; Huvelle, E.; Heurgue-Hamard, V.; Lafontaine, D.L.
The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis
Mol. Biol. Cell
26
2080-2095
2015
Homo sapiens (O43709), Homo sapiens
Manually annotated by BRENDA team
Letoquart, J.; Huvelle, E.; Wacheul, L.; Bourgeois, G.; Zorbas, C.; Graille, M.; Heurgue-Hamard, V.; Lafontaine, D.L.
Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes
Proc. Natl. Acad. Sci. USA
111
E5518-E5526
2014
Saccharomyces cerevisiae (P25627)
Manually annotated by BRENDA team
Sardana, R.; White, J.P.; Johnson, A.W.
The rRNA methyltransferase Bud23 shows functional interaction with components of the SSU processome and RNase MRP
RNA
19
828-840
2013
Saccharomyces cerevisiae
Manually annotated by BRENDA team