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2.1.1.310: 25S rRNA (cytosine2870-C5)-methyltransferase

This is an abbreviated version!
For detailed information about 25S rRNA (cytosine2870-C5)-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
cytosine2870 in 25S rRNA
=
S-adenosyl-L-homocysteine
+
5-methylcytosine2870 in 25S rRNA

Synonyms

m5C-methyltransferase, NOP2, NSUN1/Nol1, p120, proliferation-associated nucleolar antigen, protein p120, RNA:m5C-MTase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.310 25S rRNA (cytosine2870-C5)-methyltransferase

Cloned

Cloned on EC 2.1.1.310 - 25S rRNA (cytosine2870-C5)-methyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
cloning from genomic DNA, expression in a Saccharomyces cerevisiae Nop2 enzyme mutant and partial complementation. Full-length human p120 when expressed in Saccharomyces cerevisiae strongly accumulates in the nucleolus
-
cloning from genomic DNA, recombinant expression of His-tagged full-length Nop2 and Nop2(1-220) N-terminal domain in Escherichia coli strain BL21(DE3) CodonPlus
-