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BRENDA support

2.1.1.310: 25S rRNA (cytosine2870-C5)-methyltransferase

This is an abbreviated version!
For detailed information about 25S rRNA (cytosine2870-C5)-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
cytosine2870 in 25S rRNA
=
S-adenosyl-L-homocysteine
+
5-methylcytosine2870 in 25S rRNA

Synonyms

m5C-methyltransferase, NOP2, NSUN1/Nol1, p120, proliferation-associated nucleolar antigen, protein p120, RNA:m5C-MTase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.310 25S rRNA (cytosine2870-C5)-methyltransferase

Source Tissue

Source Tissue on EC 2.1.1.310 - 25S rRNA (cytosine2870-C5)-methyltransferase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
additional information
-
whereas protein p120 is almost undetectable in normal tissues, it is overexpressed in virtually all types of cancer cells. The enzyme concentration varies during the cell cycle, reaching its maximum value in the G2 phase
Manually annotated by BRENDA team