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2.1.1.319: type I protein arginine methyltransferase

This is an abbreviated version!
For detailed information about type I protein arginine methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.319

Reaction

2 S-adenosyl-L-methionine +

[protein]-L-arginine
= 2 S-adenosyl-L-homocysteine +
[protein]-Nomega,Nomega-dimethyl-L-arginine

Synonyms

arginine methyltransferase 1, CARM1, coactivator-associated arginine methyltransferase 1, coactivator-associated arginine methyltransferase 1 variant 5, EC 2.1.1.124, EC 2.1.1.125, EC 2.1.1.126, EC 2.1.1.23, Eucgr.C03665.1, PRMT I, PRMT-1, PRMT1, PRMT10, PRMT2, PRMT3, PRMT4, PRMT6, PRMT8, protein arginine methyltransferase 1, protein arginine methyltransferase 2, protein arginine methyltransferase 4, protein arginine methyltransferase 6, protein arginine methyltransferase I, protein arginine N-methyltransferase 2, protein arginine N-methyltransferase I, RMT1, Tb927.1.4690, Tb927.5.3960, type I protein arginine methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.319 type I protein arginine methyltransferase

KCat KM Value

KCat KM Value on EC 2.1.1.319 - type I protein arginine methyltransferase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.1
FYSGFNS-dimethyl-R8-P-dimethyl-R10-GRVYATSWY
pH not specified in the publication, temperature not specified in the publication
30.4
FYSGFNS-dimethyl-R8-PRG-dimethyl-R12-VYATSWY
pH not specified in the publication, temperature not specified in the publication
29.5
FYSGFNS-dimethyl-R8-PRGRVYATSWY
pH not specified in the publication, temperature not specified in the publication
-
0.3
FYSGFNSRP-dimethyl-R10-G-dimethyl-R12-VYATSWY
pH not specified in the publication, temperature not specified in the publication
17.9
FYSGFNSRP-methyl-R10-GRVYATSWY
pH not specified in the publication, temperature not specified in the publication
8.1 - 100
[GRGGFGGRGGFRGGRGG]-L-arginine
18.9
[PABPN1 mutant DeltaC20]-L-arginine
pH not specified in the publication, temperature not specified in the publication
-
26.5
[PABPN1 mutant DeltaC27]-L-arginine
pH not specified in the publication, temperature not specified in the publication
-
6.7
[PABPN1 mutant DeltaC33]-L-arginine
pH not specified in the publication, temperature not specified in the publication
-
0.1
[PABPN1 mutant DeltaC40]-L-arginine
pH not specified in the publication, temperature not specified in the publication
-
133.8
[PABPN1 mutant DELTAC8]-L-arginine
pH not specified in the publication, temperature not specified in the publication
-