2.1.1.321: type III protein arginine methyltransferase
This is an abbreviated version!
For detailed information about type III protein arginine methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.321
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2.1.1.321
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prmt7
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histone
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monomethylation
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metastasis
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monomethylarginine
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dimethylarginine
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nanog
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adomet
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medicine
- 2.1.1.321
- prmt7
- histone
-
monomethylation
- metastasis
-
monomethylarginine
- dimethylarginine
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nanog
- adomet
- medicine
Reaction
Synonyms
EC 2.1.1.124, EC 2.1.1.125, EC 2.1.1.126, EC 2.1.1.23, PRMT-7, PRMT7, protein arginine methyltransferase 7
ECTree
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Reference on EC 2.1.1.321 - type III protein arginine methyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Miranda, T.B.; Miranda, M.; Frankel, A.; Clarke, S.
PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity
J. Biol. Chem.
279
22902-22907
2004
Homo sapiens (Q9NVM4)
Jelinic, P.; Stehle, J.C.; Shaw, P.
The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation
PLoS Biol.
4
e355
2006
Homo sapiens (Q9NVM4)
Karkhanis, V.; Wang, L.; Tae, S.; Hu, Y.J.; Imbalzano, A.N.; Sif, S.
Protein arginine methyltransferase 7 regulates cellular response to DNA Damage by Methylating promoter histones H2A and H4 of the polymerase delta catalytic subunit gene, POLD1
J. Biol. Chem.
287
29801-29814
2012
Homo sapiens (Q9NVM4)
Zurita-Lopez, C.; Sandberg, T.; Kelly, R.; Clarke, S.
Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming omega-NG-monomethylated arginine residues
J. Biol. Chem.
287
7859-7870
2012
Homo sapiens (Q9NVM4), Homo sapiens
Cura, V.; Troffer-Charlier, N.; Wurtz, J.M.; Bonnefond, L.; Cavarelli, J.
Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site
Acta Crystallogr. Sect. D
70
2401-2412
2014
Mus musculus (Q922X9), Mus musculus
Feng, Y.; Maity, R.; Whitelegge, J.P.; Hadjikyriacou, A.; Li, Z.; Zurita-Lopez, C.; Al-Hadid, Q.; Clark, A.T.; Bedford, M.T.; Masson, J.Y.; Clarke, S.G.
Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions
J. Biol. Chem.
288
37010-37025
2013
Mus musculus (Q922X9), Mus musculus
Gonsalvez, G.B.; Tian, L.; Ospina, J.K.; Boisvert, F.M.; Lamond, A.I.; Matera, A.G.
Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins
J. Cell Biol.
178
733-740
2007
Homo sapiens (Q9NVM4)
Ying, Z.; Mei, M.; Zhang, P.; Liu, C.; He, H.; Gao, F.; Bao, S.
Histone arginine methylation by PRMT7 controls germinal center formation via regulating Bcl6 transcription
J. Immunol.
195
1538-1547
2015
Mus musculus (Q922X9)
Baldwin, R.M.; Haghandish, N.; Daneshmand, M.; Amin, S.; Paris, G.; Falls, T.J.; Bell, J.C.; Islam, S.; Cote, J.
Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression
Oncotarget
6
3013-3032
2015
Homo sapiens (Q9NVM4), Homo sapiens
Jain, K.; Clarke, S.G.
PRMT7 as a unique member of the protein arginine methyltransferase family A review
Arch. Biochem. Biophys.
665
36-45
2019
Trypanosoma brucei brucei (Q582G4), Mus musculus (Q922X9), Homo sapiens (Q9NVM4), Caenorhabditis elegans (Q9XW42), Trypanosoma brucei brucei 927 (Q582G4)
Hadjikyriacou, A.; Clarke, S.G.
Caenorhabditis elegans PRMT-7 and PRMT-9 are evolutionarily conserved protein arginine methyltransferases with distinct substrate specificities
Biochemistry
56
2612-2626
2017
Caenorhabditis elegans (Q9XW42), Caenorhabditis elegans
Vuong, T.A.; Jeong, H.J.; Lee, H.J.; Kim, B.G.; Leem, Y.E.; Cho, H.; Kang, J.S.
PRMT7 methylates and suppresses GLI2 binding to SUFU thereby promoting its activation
Cell Death Differ.
27
15-28
2020
Mus musculus (Q922X9), Mus musculus
Liu, F.; Wan, L.; Zou, H.; Pan, Z.; Zhou, W.; Lu, X.
PRMT7 promotes the growth of renal cell carcinoma through modulating the beta-catenin/C-MYC axis
Int. J. Biochem. Cell Biol.
120
105686
2020
Homo sapiens (Q9NVM4)
Chen, T.Y.; Lee, S.H.; Dhar, S.S.; Lee, M.G.
Protein arginine methyltransferase 7-mediated microRNA-221 repression maintains Oct4, Nanog, and Sox2 levels in mouse embryonic stem cells
J. Biol. Chem.
293
3925-3936
2018
Mus musculus (Q922X9), Mus musculus
Thakur, A.; Hevel, J.M.; Acevedo, O.
Examining product specificity in protein arginine methyltransferase 7 (PRMT7) using quantum and molecular mechanical simulations
J. Chem. Inf. Model.
59
2913-2923
2019
Trypanosoma brucei brucei (Q582G4), Trypanosoma brucei brucei 927 (Q582G4)
Li, F.; Zhu, H.; Hou, M.; Zhang, X.; Li, Z.; Zhao, H.; Zhou, Q.; Zhong, X.
Identification, expression and functional analysis of prmt7 in medaka Oryzias latipes
J. Exp. Zool. B Mol. Dev. Evol.
334
77-87
2020
Oryzias latipes (H2MJK7)
Verma, M.; Charles, R.C.M.; Chakrapani, B.; Coumar, M.S.; Govindaraju, G.; Rajavelu, A.; Chavali, S.; Dhayalan, A.
PRMT7 interacts with ASS1 and citrullinemia mutations disrupt the interaction
J. Mol. Biol.
429
2278-2289
2017
Homo sapiens (Q9NVM4)
Haghandish, N.; Baldwin, R.M.; Morettin, A.; Dawit, H.T.; Adhikary, H.; Masson, J.Y.; Mazroui, R.; Trinkle-Mulcahy, L.; Cote, J.
PRMT7 methylates eukaryotic translation initiation factor 2alpha and regulates its role in stress granule formation
Mol. Biol. Cell
30
778-793
2019
Homo sapiens (Q9NVM4)
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