2.1.1.33: tRNA (guanine46-N7)-methyltransferase
This is an abbreviated version!
For detailed information about tRNA (guanine46-N7)-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.33
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2.1.1.33
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methyltransferase-like
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n7-methylguanosine
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cyp27b1
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mettl21b
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trnaphe
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mescs
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kidney-specific
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methylome
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submodules
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methyl-transfer
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pharmacology
- 2.1.1.33
-
methyltransferase-like
-
n7-methylguanosine
- cyp27b1
-
mettl21b
- trnaphe
-
mescs
-
kidney-specific
-
methylome
-
submodules
-
methyl-transfer
- pharmacology
Reaction
Synonyms
7-methylguanine transfer ribonucleate methylase, m7G-methyltransferase, m7G46 methyltransferase Trm8p/Trm82p, methyltransferase like 1, methyltransferase, transfer ribonucleate guanine 7-, METTL1, N7-methylguanine methylase, PA14_05000, transfer ribonucleate guanine 7-methyltransferase, transfer RNA (m7G46) methyltransferase, Trm8–Trm82 complex, TrmB, TrMet (m7G46), tRNA (m7G46) methyltransferase, tRNA guanine 7-methyltransferase
ECTree
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Cloned
Cloned on EC 2.1.1.33 - tRNA (guanine46-N7)-methyltransferase
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expressed in a wheat germ cell-free translation system, active Trm8-Trm82 heterodimer is only synthesized under conditions, in which both Trm8 and Trm82 mRNAs are cotranslated
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ORF YDL201w encodes Trm8 and ORF YDR165w encodes Trm82, both proteins form a complex with m7G-methyltransferase activity, Trm8 contains a binding domain for S-adenosyl-L-methionine: GXGXG, coexpression of Trm8/Trm82 in Escherichia coli BL21 Codon Plus (DE3) as His6-fusion proteins under control of the Ptac-promoter
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