2.1.1.41: sterol 24-C-methyltransferase

This is an abbreviated version!
For detailed information about sterol 24-C-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.41

2.1.1.41

ergosterol

leishmaniasis

lanosterol

infantum

medicine

tomatidine

24-alkyl

drug development

24-ethyl

c24-methylation

agriculture

c1-transfer

degradation

Reaction

24-methylene-5alpha-cholest-8-en-3beta-ol

Synonyms

(S)-adenosyl-L-methionine:DELTA24(25)-sterol methyl transferase, 24-C-sterol methyltransferase, 24-SMT, 24-sterol C-methyltransferase, C-24 sterol methyltransferase, C24-methyltransferase, DELTA(24,25)-SMT, DELTA24-methyltransferase, DELTA24-sterol methyltransferase, Erg6, Erg6p, LMJF_36_2380, LMJF_36_2390, methyltransferase, DELTA24-sterol, PbSMT, phytosterol methyltransferase, S-adenosyl-4-methionine:sterol DELTA24-methyltransferase, S-adenosyl-L-methionine:DELTA24(23)-sterol methyltransferase, SAM:SMT, SMT, SMT protein, SMT1, SMT80, SMT90, sterol 24-C-methyltransferase, sterol C24-methyltransferase, sterol methyltransferase, STM, TbSMT, zymosterol 24-methyltransferase, zymosterol-24-methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.41 sterol 24-C-methyltransferase

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Results	in table
6	Activating Compound
191	AA Sequence
12	Application
1	CAS Registry Number
15	Cloned(Commentary)
5	Cofactor
5	General Information
1	General Stability
8	IC50 Value
106	Inhibitors
6	kcat/KM [mM/s]
64	Ki Value [mM]
59	KM Value [mM]
12	Localization
2	Metals/Ions
8	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
52	Organism
6	Pathway
15	pH Optimum
7	pH Range
205	Protein Variants
17	Purification (Commentary)
18	Reaction
1	Reaction Type
47	Reference
5	Source Tissue
13	Specific Activity [micromol/min/mg]
2	Storage Stability
114	Substrates and Products (Substrate)
6	Subunits
82	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
2	Temperature Range [°C]
36	Turnover Number [1/s]

Application

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Application on EC 2.1.1.41 - sterol 24-C-methyltransferase

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agriculture

2 entries

degradation

Saccharomyces cerevisiae

active site of the yeast SMT has the necessary amino acids to generate products common to SMT catalysis of plants and protozoa, minor perturbations in the active site topography brought about by mutagenesis are sufficient to recognize new substrates

671933

drug development

5 entries

medicine

4 entries