2.1.1.41: sterol 24-C-methyltransferase
This is an abbreviated version!
For detailed information about sterol 24-C-methyltransferase, go to the full flat file.
Reaction
S-adenosyl-L-methionine +
5alpha-cholesta-8,24-dien-3beta-ol=
S-adenosyl-L-homocysteine +
24-methylene-5alpha-cholest-8-en-3beta-ol
Synonyms
(S)-adenosyl-L-methionine:DELTA24(25)-sterol methyl transferase, 24-C-sterol methyltransferase, 24-SMT, 24-sterol C-methyltransferase, C-24 sterol methyltransferase, C24-methyltransferase, DELTA(24,25)-SMT, DELTA24-methyltransferase, DELTA24-sterol methyltransferase, Erg6, Erg6p, LMJF_36_2380, LMJF_36_2390, methyltransferase, DELTA24-sterol, PbSMT, phytosterol methyltransferase, S-adenosyl-4-methionine:sterol DELTA24-methyltransferase, S-adenosyl-L-methionine:DELTA24(23)-sterol methyltransferase, SAM:SMT, SMT, SMT protein, SMT1, SMT80, SMT90, sterol 24-C-methyltransferase, sterol C24-methyltransferase, sterol methyltransferase, STM, TbSMT, zymosterol 24-methyltransferase, zymosterol-24-methyltransferase
ECTree
KM Value
KM Value on EC 2.1.1.41 - sterol 24-C-methyltransferase
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0.018
24(28)-methylene cycloartenol
pH 7.5, 30°C
0.022
24(28)-methylene lophenol
pH 7.5, 30°C
0.019
24-methylenelanosterol
-
recombinant enzyme
0.019
26,27-dehydrolanosterol
-
pH 7.5, 37°C, Vmax: 6 pmol/min
0.013 - 0.074
26,27-dehydrozymosterol
0.035
31-norlanosterol
-
pH 7.5, 37°C, Vmax 45 pmol/min
0.025
Cycloartenol
pH 7.5, 30°C
0.236 - 0.281
desmosterol
0.0106 - 0.038
lanosterol
0.02
obtusifoliol
pH 7.5, 30°C
0.0334
S-adenosyl-L-methionine
-
-
additional information
additional information
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0.013
26,27-dehydrozymosterol
-
mutant E64L
0.015
26,27-dehydrozymosterol
-
mutant D65L
0.015 - 0.017
26,27-dehydrozymosterol
-
wild-type
0.017
26,27-dehydrozymosterol
-
mutant D79L
0.022
26,27-dehydrozymosterol
-
wild-type
0.022
26,27-dehydrozymosterol
-
mutant E82L
0.023
26,27-dehydrozymosterol
-
mutant Y81A
0.023
26,27-dehydrozymosterol
-
mutant Y81W
0.024
26,27-dehydrozymosterol
-
mutant Y81L
0.024
26,27-dehydrozymosterol
-
mutant Y81V
0.026
26,27-dehydrozymosterol
-
mutant Y81F
0.027
26,27-dehydrozymosterol
-
mutant Y81I
0.074
26,27-dehydrozymosterol
-
mutant E98L
0.016
AdoMet
-
mutant Tyr153Phe
0.017
AdoMet
-
mutant Tyr153Leu
0.03
AdoMet
-
mutant Cys128Ser
0.236
desmosterol
-
-
0.0106
lanosterol
-
recombinant enzyme
0.024
lanosterol
pH 7.5, 30°C
0.038
lanosterol
-
pH 7.5, 37°C, Vmax: 50 pmol/min
0.006
Zymosterol
-
mutant Y66F, pH not specified in the publication, 35°C
0.01
Zymosterol
-
mutant Y177F, pH not specified in the publication, 35°C
0.011
Zymosterol
-
pH 7.5, 32°C, mutant enzyme H107L
0.017
Zymosterol
-
wild-type
0.017
Zymosterol
-
pH 7.5, 32°C, mutant enzyme D189L
0.017
Zymosterol
-
pH 7.5, 32°C, mutant enzyme E224L
0.017
Zymosterol
-
pH 7.5, 32°C, wild-type enzyme
0.017
Zymosterol
-
mutant Y81F
0.017
Zymosterol
-
mutant Y81W
0.018
Zymosterol
-
mutant Y81A
0.018
Zymosterol
-
mutant Y81L
0.02
Zymosterol
-
pH 7.5, 32°C, mutant enzyme H238L
0.021
Zymosterol
-
mutant Y81I
0.024
Zymosterol
-
pH 7.5, 32°C, mutant enzyme H199L
0.026
Zymosterol
-
mutant Y81V
0.03
Zymosterol
-
pH 7.5, 37°C, Vmax 2 pmol/min
0.034
Zymosterol
-
pH 7.5, 32°C, mutant enzyme E108L
0.034
Zymosterol
-
pH 7.5, 32°C, mutant enzyme E209L
0.036
Zymosterol
-
mutant Y208F, pH not specified in the publication, 35°C
0.042
Zymosterol
-
pH 7.5, 32°C, mutant enzyme E246L
0.05
Zymosterol
-
pH 7.5, 30°C
0.055
Zymosterol
-
wild-type, pH not specified in the publication, 35°C
0.055 - 0.075
Zymosterol
-
value depends on concentration of detergent
additional information
additional information
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-
-
additional information
additional information
-
overview
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2.1.1.41 sterol 24-C-methyltransferase
results (
results (
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