2.1.1.60: calmodulin-lysine N-methyltransferase
This is an abbreviated version!
For detailed information about calmodulin-lysine N-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.60
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2.1.1.60
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calmodulins
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trimethylated
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unmethylated
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calmodulin-dependent
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facial
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calmidazolium
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panic
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phobias
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hypotonia
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dysmorphic
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trimethyllysine
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paramecium
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cystinuria
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calcium-depleted
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calmodulin-binding
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dsm-based
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calmodulin-sepharose
- 2.1.1.60
- calmodulins
-
trimethylated
-
unmethylated
-
calmodulin-dependent
-
facial
- calmidazolium
-
panic
-
phobias
-
hypotonia
-
dysmorphic
- trimethyllysine
- paramecium
-
cystinuria
-
calcium-depleted
-
calmodulin-binding
-
dsm-based
-
calmodulin-sepharose
Reaction
Synonyms
calmodulin lysine methyl transferase, calmodulin lysine methyltransferase, calmodulin lysine N-methyltransferase, calmodulin methyltransferase, calmodulin N-methyltransferase, calmodulin-lysine N-methyltransferase, CaM KMT, CaM Lys methyltransferase, CaMKMT, methyltransferase, calmodulin (lysine), S-adenosylmethionine:calmodulin N-methyltransferase (lysine)
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General Information
General Information on EC 2.1.1.60 - calmodulin-lysine N-methyltransferase
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malfunction
metabolism
the enzyme is the major methyltransferase of calmodulin in human cells and a Hsp90 client protein
physiological function
the enzyme is essential for normal body growth and somatosensory development, as well as for the proper functioning of the adult mouse brain
enzyme-deficient mice have deficits in motor learning, complex coordination and learning of aversive stimuli
malfunction
the absence of enzyme causes accumulation of hypomethylated calmodulin in 2p21 deletion syndrome patients