2.1.1.61: tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase

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For detailed information about tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase, go to the full flat file.

Reaction

Synonyms

5-methylaminomethyl-2-thiouridylate methyltransferase, 5-methylaminomethyl-2-thiouridylate-methyltransferase, methylaminomethyl-2-thiouridylate-methyltransferase, methyltransferase, transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-, MTO2, MTU1, S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase, transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase, TRMU, tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase, tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase, tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.61 tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase

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Results	in table
2	Activating Compound
8785	AA Sequence
2	Application
1	CAS Registry Number
3	Cloned(Commentary)
16	Disease/ Diagnostics
1	Expression
3	General Information
4	Inhibitors
8	Localization
1	Metals/Ions
3	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
185	Organism
1	Pathway
8	PDB ID
1	pH Optimum
1	pI Value
8	Protein Variants
3	Purification (Commentary)
2	Reaction
1	Reaction Type
10	Reference
20	Source Tissue
2	Specific Activity [micromol/min/mg]
10	Substrates and Products (Substrate)
3	Subunits
20	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Stability [°C]
1	Turnover Number [1/s]

Disease

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Disease on EC 2.1.1.61 - tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Liver Failure

Hepatic Copper Accumulation: A Novel Feature in Transient Infantile Liver Failure Due to TRMU Mutations?

25665837

Liver Failure

Reversible infantile mitochondrial diseases.

25407320

Liver Failure, Acute

Hepatic Copper Accumulation: A Novel Feature in Transient Infantile Liver Failure Due to TRMU Mutations?

25665837

Liver Failure, Acute

Leigh syndrome associated with TRMU gene mutations.

33365252

Mitochondrial Diseases

Altered 2-thiouridylation impairs mitochondrial translation in reversible infantile respiratory chain deficiency.

23814040

Mitochondrial Diseases

Reversible infantile mitochondrial diseases.

25407320

Mitochondrial Myopathies

Reversible infantile mitochondrial diseases.

25407320

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