2.1.1.64: 3-demethylubiquinol 3-O-methyltransferase
This is an abbreviated version!
For detailed information about 3-demethylubiquinol 3-O-methyltransferase, go to the full flat file.
Reaction
Synonyms
2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase, 5-demethylubiquinone-9 methyltransferase, 5-demethylubiquinone-9-methyltransferase, AtCOQ3, COQ3, Coq3 O-methyltransferase, O-methyltransferase, OMHMB methyltransferase, OMHMB-methyltransferase, S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase, UbiG, UbiG methyltransferase, ubiquinone biosynthesis O-methyltransferase
ECTree
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General Information
General Information on EC 2.1.1.64 - 3-demethylubiquinol 3-O-methyltransferase
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malfunction
physiological function
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after 1 h of H2O2 treatment, the viability of the strain defective in ubiG is reduced 28fold compared to the corresponding wild-type. When treated with CuSO4, the viability of the the strain defective in ubiG (HW271), is reduced 4.4fold after 30 min compared to its isogenic wild-type
malfunction
rat COQ3 gene restores O-methyltransferase activity in coq3 null mutant yeast
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the ubiG gene product is essential for growth on glycerol minimal medium
physiological function
the membrane-binding region of UbiG gates the entrance of methyl donor. When bound with liposome, UbiG displays an enhanced binding ability toward the methyl donor product S-adenosylhomocysteine