2.1.1.75: apigenin 4'-O-methyltransferase
This is an abbreviated version!
For detailed information about apigenin 4'-O-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.75
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2.1.1.75
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luteolin
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quercetin
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eriodictyol
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phenylpropanoid
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naringenin
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regioselectivity
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kaempferol
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regiospecific
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flavonols
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7-o-methyltransferase
- 2.1.1.75
- luteolin
- quercetin
- eriodictyol
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phenylpropanoid
- naringenin
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regioselectivity
- kaempferol
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regiospecific
- flavonols
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7-o-methyltransferase
Reaction
Synonyms
F4'OMT, flavonoid O-methyltransferase, FOMT3, FOMT5, methyltransferase, flavonoid
ECTree
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Substrates Products
Substrates Products on EC 2.1.1.75 - apigenin 4'-O-methyltransferase
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REACTION DIAGRAM
S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone
S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone
S-adenosyl-L-methionine + genistein
?
less than 1% activity compared to apigenin
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-
?
S-adenosyl-L-methionine + genkwanin
S-adenosyl-L-homocysteine + apigenin-7,4'-dimethyl ether
S-adenosyl-L-methionine + kaempferol
?
about 10% activity compared to apigenin
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-
?
S-adenosyl-L-methionine + luteolin
?
about 35% activity compared to apigenin
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-
?
S-adenosyl-L-methionine + naringenin
?
less than 1% activity compared to apigenin
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-
?
S-adenosyl-L-methionine + quercetin
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about 10% activity compared to apigenin
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-
?
S-adenosyl-L-methionine + scutellarein
?
about 18% activity compared to apigenin
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-
?
S-adenosyl-L-methionine + scutellarein-7-methyl ether
S-adenosyl-L-homocysteine + ladanein
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?
S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone
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i.e. apigenin
i.e. acacetin
?
S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone
S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone
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enzyme is involved in biosynthesis of 4'-methoxylated flavonoids
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-
?
S-adenosyl-L-homocysteine + acacetin
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?
S-adenosyl-L-methionine + apigenin
S-adenosyl-L-homocysteine + acacetin
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?
S-adenosyl-L-methionine + apigenin
S-adenosyl-L-homocysteine + acacetin
100% activity
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-
?
S-adenosyl-L-homocysteine + apigenin-7,4'-dimethyl ether
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?
S-adenosyl-L-methionine + genkwanin
S-adenosyl-L-homocysteine + apigenin-7,4'-dimethyl ether
about 10% activity compared to apigenin
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-
?
?
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no activity with baicalein, acacetin, caffeic acid, caffeoyl aldehyde, caffeoyl alcohol, 5-hydroxyconiferyl aldehyde, and 5-hydroxyconiferyl alcohol
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additional information
?
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no activity with baicalein, acacetin, caffeic acid, caffeoyl aldehyde, caffeoyl alcohol, 5-hydroxyconiferyl aldehyde, and 5-hydroxyconiferyl alcohol
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