2.1.2.1: glycine hydroxymethyltransferase

This is an abbreviated version!
For detailed information about glycine hydroxymethyltransferase, go to the full flat file.

Word Map on EC 2.1.2.1

2.1.2.1

one-carbon

pyridoxal

thymidylate

purine

5'-phosphate

homocysteine

dihydrofolate

folate-dependent

photorespiratory

photorespiration

folate-mediated

pyridoxal-5'-phosphate

thf

dtmp

mthfd1

plp-dependent

remethylation

aldimine

phgdh

medicine

folate-metabolizing

5,10-methenyltetrahydrofolate

5'-phosphate-dependent

antifolate

hydroxypyruvate

quinonoid

5-methyltetrahydrofolate

glycerate

5-formyltetrahydrofolate

drug development

folate-related

d-alanine

c1-tetrahydrofolate

1-carbon

5-formyl

polyglutamate

l-threonine

alpha-protons

slc19a1

retro-aldol

degradation

analysis

synthesis

biotechnology

pharmacology

Reaction

Synonyms

AtSHMT3, bsSHMT, bstSHMT, EC 4.1.2.6, eSHMT, GlyA, GlyA protein, glycine hydroxymethyltransferrase, hSHMT, L-serine hydroxymethyltransferase, mitochondrial serine hydroxymethyltransferase, MJ1597, PvSHMT, Rhg4, serine hydroxymethyl transferase, serine hydroxymethylase hydroxymethyltransferase, serine, serine hydroxymethyltransferase, serine hydroxymethyltransferase 1, serine hydroxymethyltransferase 2, serine hydroxymethyltransferase 2alpha, serine transhydroxymethylase, serine:H4F hydroxymethyltransferase, serine:tetrahydrofolate hydroxymethyltransferase, SHM1, SHM2, SHMT, SHMT-1, SHMT-L, SHMT-S, SHMT08, SHMT1, SHMT2, SHMT2alpha, SHMT3, zcSHMT, zebrafish cytosolic serine hydroxymethyltransferase, zebrafish mitochondiral serine hydroxymethyltransferase, zmSHMT

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.2 Hydroxymethyl-, formyl- and related transferases

2.1.2.1 glycine hydroxymethyltransferase

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Results	in table
12	Activating Compound
57530	AA Sequence
55	Application
1	CAS Registry Number
84	Cloned(Commentary)
203	Cofactor
22	Crystallization (Commentary)
984	Disease/ Diagnostics
8	Expression
107	General Information
24	General Stability
26	IC50 Value
314	Inhibitors
50	kcat/KM [mM/s]
33	Ki Value [mM]
179	KM Value [mM]
129	Localization
20	Metals/Ions
102	Molecular Weight [Da]
191	Natural Substrates/ Products (Substrates)
571	Organism
28	Pathway
280	PDB ID
44	pH Optimum
16	pH Range
14	pH Stability
1	pI Value
6	Posttranslational Modification
92	Protein Variants
71	Purification (Commentary)
50	Reaction
1	Reaction Type
241	Reference
2	Renatured (Commentary)
95	Source Tissue
69	Specific Activity [micromol/min/mg]
13	Storage Stability
498	Substrates and Products (Substrate)
137	Subunits
345	Synonyms
1	Systematic Name
29	Temperature Optimum [°C]
17	Temperature Range [°C]
49	Temperature Stability [°C]
111	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 2.1.2.1 - glycine hydroxymethyltransferase

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5,6,7,8-tetrahydrofolate

Corynebacterium glutamicum

control of SHMT activity by the availability of 5,6,7,8-tetrahydrofolate

CO(NH2)2

activates

EDTA

L-serine

stabilizes the dimeric form of the enzyme

718984

pyridoxal 5'-phosphate

3 entries

pyridoxal phosphate

Trichomonas vaginalis

673412

additional information

4 entries