2.1.2.7: D-alanine 2-hydroxymethyltransferase

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For detailed information about D-alanine 2-hydroxymethyltransferase, go to the full flat file.

Reaction

Synonyms

2-methylserine hydroxymethyltransferase, alpha-methylserine hydroxymethyltransferase, hydroxymethyltransferase, 2-methylserine, MSHMT

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.2 Hydroxymethyl-, formyl- and related transferases

2.1.2.7 D-alanine 2-hydroxymethyltransferase

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Results	in table
3	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
5	Cofactor
2	Crystallization (Commentary)
4	General Stability
18	Inhibitors
6	Ki Value [mM]
12	KM Value [mM]
3	Localization
2	Molecular Weight [Da]
9	Organism
2	Pathway
4	pH Optimum
1	pH Range
2	pH Stability
4	Purification (Commentary)
1	Reaction
1	Reaction Type
8	Reference
6	Specific Activity [micromol/min/mg]
22	Substrates and Products (Substrate)
2	Subunits
7	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]

Reference

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Reference on EC 2.1.2.7 - D-alanine 2-hydroxymethyltransferase

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485776

Wilson Miles, E.

alpha-Methylserine transhydroxymethylase (Pseudomonas)

Methods Enzymol.

17B

341-346

1971

Pseudomonas sp.

485777

Wilson, E.M.; Snell, E.E.

Metabolism of alpha-methylserine. I. Alpha-methylserine hydroxymethyltransferase

J. Biol. Chem.

237

3171-3179

1962

Pseudomonas sp., Pseudomonas sp. MS

14001018

485778

Wilson, E.M.; Snell, E.E.

Metabolism of alpha-methylserine. II. Stereospecificity of alpha-methylserine hydroxymethyltransferase

J. Biol. Chem.

237

3180-3184

1962

Pseudomonas sp.

14001019

485779

Sperl, G.T.

Microbial metabolism of 2-methyl amino acids

Curr. Microbiol.

135-138

1989

Clostridium tetanomorphum, Escherichia coli

702735

Nozaki, H.; Kuroda, S.; Watanabe, K.; Yokozeki, K.

Cloning of the gene encoding alpha-methylserine hydroxymethyltransferase from Aminobacter sp. AJ110403 and Ensifer sp. AJ110404 and characterization of the recombinant enzyme

Biosci. Biotechnol. Biochem.

3002-3005

2008

Aminobacter sp. AJ110403 (B2DEU8), Ensifer sp. AJ110404 (B2DEV1)

18997407