2.1.3.10: malonyl-S-ACP:biotin-protein carboxyltransferase

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For detailed information about malonyl-S-ACP:biotin-protein carboxyltransferase, go to the full flat file.

Reaction

Synonyms

acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase, MadC,D, malonyl-S-acyl-carrier protein:biotin-protein carboxyltransferase, malonyl-[acyl-carrier protein]:biotinyl-[protein] carboxyltransferase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.3 Carboxy- and carbamoyltransferases

                2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase

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Results	in table
224	AA Sequence
1	CAS Registry Number
2	Inhibitors
2	Ki Value [mM]
4	KM Value [mM]
2	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
1	Organism
1	Pathway
16	PDB ID
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
1	Reference
1	Specific Activity [micromol/min/mg]
5	Substrates and Products (Substrate)
1	Subunits
4	Synonyms
1	Systematic Name

Natural Substrates Products

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Natural Substrates Products on EC 2.1.3.10 - malonyl-S-ACP:biotin-protein carboxyltransferase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

acetyl-CoA + dephospho-CoA

CoA + acetyl-dephospho-CoA

Malonomonas rubra

-

-

684745

-

-

r

malonyl-CoA + dephospho-CoA

CoA + malonyl-dephospho-CoA

Malonomonas rubra

-

-

684745

-

-

r

additional information

?

-

Malonomonas rubra

-

enzyme catalyzes the transfer of acyl carrier protein from acetyl acyl carrier protein and malonate to yield malonyl acyl carrier protein and acetate. Malonate is thus activated on the enzyme by exchange for the catalytically important enzyme-bound acetyl thioester residues

684745

-

-

?