2.1.4.2: scyllo-inosamine-4-phosphate amidinotransferase

This is an abbreviated version!
For detailed information about scyllo-inosamine-4-phosphate amidinotransferase, go to the full flat file.

Word Map on EC 2.1.4.2

2.1.4.2

histone

heat-stable

enteroaggregative

diarrheic

sta

stool

succinylation

piglets

enterotoxin

farm

gnotobiotic

succinyltransferase

heat-labile

adhesins

colibacillosis

chilean

pathotypes

lncrnas

succinyl-coa

enterotoxigenic

Reaction

1-amino-1-deoxy-scyllo-inositol 4-phosphate

1-guanidino-1-deoxy-scyllo-inositol 4-phosphate

Synonyms

aminocyclitolamidinotransferase, arginine:Xamidinotransferase, inosamine-P-amidinotransferase, inosamine-phosphate amidinotransferase, L-arginine:inosamine phosphate amidinotransferase, L-arginine:inosamine-P-amidinotransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.4 Amidinotransferases

2.1.4.2 scyllo-inosamine-4-phosphate amidinotransferase

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Results	in table
125	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
1	Crystallization (Commentary)
10	Inhibitors
3	Molecular Weight [Da]
42	Natural Substrates/ Products (Substrates)
50	Organism
3	Pathway
2	PDB ID
6	Purification (Commentary)
2	Reaction
1	Reaction Type
42	Reference
22	Source Tissue
1	Specific Activity [micromol/min/mg]
138	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name

Reference

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Reference on EC 2.1.4.2 - scyllo-inosamine-4-phosphate amidinotransferase

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485964

Walker, J.B.

Amidinotranferases

The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )

497-509

1973

Streptomyces bikiniensis, Streptomyces bluensis, Streptomyces galbus, Streptomyces griseocarneus, Streptomyces griseus, Streptomyces humidus, Streptomyces hygroscopicus

485971

Guthmiller, P.; Van Pilsum, J.F.; Boen, J.R.; McGuire, D.M.

Cloning and sequencing of rat kidney L-arginine:glycine amidinotransferase. Studies on the mechanism of regulation by growth hormone and creatine

J. Biol. Chem.

269

17556-17560

1994

Streptomyces griseus

8021264

485973

Humm, A.; Fritsche, E.; Mann, K.; Goehl, M.; Huber, R.

Recombinant expression and isolation of human L-arginine:glycine amidinotransferase and identification of its active-site cysteine residue

Biochem. J.

322

771-776

1997

Streptomyces griseus

485976

Bedekar, A.; Zink, R.M.; Sherman, D.H.; Line, T.V.; Van Pilsum, J.F.

The comparative amino acid sequences, substrate specificities and gene or cDNA nucleotide sequences of some prokaryote and eukaryote amidinotransferases: implications for evolution

Comp. Biochem. Physiol. B

119B

677-690

1998

Streptomyces consensus, Streptomyces galbus, Streptomyces galbus (Q54256), Streptomyces griseus, Streptomyces griseus (P08078), Streptomyces griseus strB2 (P29780), Streptomyces bluensis (Q53814), Streptomyces glaucescens strB1 (Q54258), Streptomyces glaucescens strB2 (Q54264), Streptomyces griseus SPH, Streptomyces griseus ATCC 10137

485977

Fritsche, E.; Humm, A.; Huber, R.

The ligand-induced structural changes of human L-arginine:glycine amidinotransferase. A mutational and crystallographic study

J. Biol. Chem.

274

3026-3032

1999

Streptomyces griseus

9915841

485981

Walker, M.S.; Walker, J.B.

Enzymic studies on the biosynthesis of streptomycin

J. Biol. Chem.

241

1262-1270

1966

no activity in Streptomyces griseus, Streptomyces bikiniensis, Streptomyces bluensis, Streptomyces griseocarneus, Streptomyces griseus, Streptomyces kanamyceticus, no activity in Streptomyces griseus ATCC 10971, Streptomyces griseus W4

5935341

485983

Walker, J.B.

Biosynthesis of the monoguanidinated inositol moiety of bluensomycin, a possible evolutionary precursor of streptomycin

J. Biol. Chem.

249

2397-2404

1974

Streptomyces hygroscopicus

4132552

485984

Walker, J.B.

L-Arginine:inosamine-P amindinotransferase (s)

Methods Enzymol.

451-458

1975

Streptomyces bikiniensis, Streptomyces galbus, Streptomyces griseocarneus, Streptomyces humidus, Streptomyces hygroscopicus, Streptomyces ornatus

1134367

485985

Tohyama, H.; Okami, Y.; Umezawa, H.

Nucleotide sequence of the streptomycinphosphotransferase and amidinotransferase from Streptomyces griseus

Nucleic acids Res.

1819-1833

1987

Streptomyces bikiniensis, Streptomyces griseus

3029728

485989

Fritsche, E.; Bergner, A.; Humm, A.; Piepersberg, W.; Huber, R.

Crystal Structure of L-Arginine:Inosamine-Phosphate Amidinotransferase StrB1 from Streptomyces griseus: An Enzyme Involved in Streptomycin Biosynthesis

Biochemistry

17664-17672

1998

Streptomyces galbus, Streptomyces griseus, Streptomyces griseus (P08078), Streptomyces griseus strB1 (P08078), Streptomyces glaucescens strB1 (Q54258), Streptomyces glaucescens strB2 (Q54264), Streptomyces galbus strB1

9922132