2.2.1.3: formaldehyde transketolase

This is an abbreviated version!
For detailed information about formaldehyde transketolase, go to the full flat file.

Reaction

Synonyms

DAS, DAS1, DHAS, dihydroxyacetone synthase, peroxisomal transketolase, synthase, dihydroxyacetone, transketolase, formaldehyde

ECTree

     2 Transferases

         2.2 Transferring aldehyde or ketonic groups

             2.2.1 Transketolases and transaldolases

                2.2.1.3 formaldehyde transketolase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
29	AA Sequence
2	CAS Registry Number
5	Cloned(Commentary)
5	Cofactor
6	General Information
12	General Stability
28	Inhibitors
6	KM Value [mM]
8	Localization
10	Metals/Ions
15	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
44	Organism
4	Pathway
7	pH Optimum
2	pH Range
1	Posttranslational Modification
1	Protein Variants
8	Purification (Commentary)
2	Reaction
1	Reaction Type
27	Reference
8	Specific Activity [micromol/min/mg]
8	Storage Stability
78	Substrates and Products (Substrate)
11	Subunits
17	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
9	Temperature Stability [°C]

Substrates Products

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Substrates Products on EC 2.2.1.3 - formaldehyde transketolase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Substrate/Product Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

acetaldehyde + D-xylulose 5-phosphate

glyceraldehyde 3-phosphate + 1,3-dihydroxybutane-2-one

Acinetobacter sp.

-

-

486057

-

-

?

D-erythrose 4-phosphate + D-xylulose 5-phosphate

D-fructose 6-phosphate + glyceraldehyde 3-phosphate

Acinetobacter sp.

-

-

486057

-

-

?

D-ribose 5-phosphate + formaldehyde

?

Acinetobacter sp.

-

-

486057

-

-

?

D-xylulose 5-phosphate + butyraldehyde

glyceraldehyde 3-phosphate + 1,3-dihydroxyhexane-2-one

[Candida] boidinii

-

-

486051

-

-

?

D-xylulose 5-phosphate + D-erythrose

glyceraldehyde 3-phosphate + D-fructose

[Candida] boidinii

-

-

486051

-

-

?

D-xylulose 5-phosphate + D-glucose

glyceraldehyde 3-phosphate + D-glycero-D-ido-oct-2-ulose

[Candida] boidinii

-

-

486051

-

-

?

D-xylulose 5-phosphate + D-glyceraldehyde

glyceraldehyde 3-phosphate + D-xylulose

3 entries

D-xylulose 5-phosphate + D-ribose

glyceraldehyde 3-phosphate + sedoheptulose

[Candida] boidinii

-

-

486051

-

-

?

D-xylulose 5-phosphate + formaldehyde

D-glyceraldehyde 3-phosphate + glycerone

4 entries

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

28 entries

D-xylulose 5-phosphate + glycolaldehyde

glyceraldehyde 3-phosphate + 1,3,5-trihydroxypentane-2-one

2 entries

D-xylulose 5-phosphate + heptaldehyde

glyceraldehyde 3-phosphate + 1,3-dihydroxynonane-2-one

[Candida] boidinii

-

-

486051

-

-

?

D-xylulose 5-phosphate + propionaldehyde

glyceraldehyde 3-phosphate + 1,3-dihydroxypentane-2-one

[Candida] boidinii

-

-

486051

-

-

?

D-xylulose 5-phosphate + ribose 5-phosphate

glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate

2 entries

fructose 6-phosphate + formaldehyde

dihydroxyacetone + erythrose 4-phosphate

6 entries

glucose 6-phosphate + formaldehyde

?

Acinetobacter sp.

-

-

486057

-

-

?

glycolaldehyde + D-xylulose 5-phosphate

glyceraldehyde 3-phosphate + 1,3-dihydroxypentane-2-one

Acinetobacter sp.

-

-

486057

-

-

?

hydroxypyruvate + formaldehyde

CO2 + dihydroxyacetone

5 entries

ribulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + 1,3-dihydroxyacetone

Acinetobacter sp.

-

-

486057

-

-

?

sedoheptulose 7-phosphate + formaldehyde

dihydroxyacetone + ribose

3 entries

additional information

?

-

3 entries

D-xylulose 5-phosphate + D-glyceraldehyde

glyceraldehyde 3-phosphate + D-xylulose

Acinetobacter sp.

-

-

486057

-

-

?

D-xylulose 5-phosphate + D-glyceraldehyde

glyceraldehyde 3-phosphate + D-xylulose

[Candida] boidinii

-

-

486048

-

-

?

D-xylulose 5-phosphate + D-glyceraldehyde

glyceraldehyde 3-phosphate + D-xylulose

[Candida] boidinii KD1

-

-

486048

-

-

?

D-xylulose 5-phosphate + formaldehyde

D-glyceraldehyde 3-phosphate + glycerone

Ogataea polymorpha

-

-

756248

-

-

?

D-xylulose 5-phosphate + formaldehyde

D-glyceraldehyde 3-phosphate + glycerone

Ogataea polymorpha NCYC495

-

-

756248

-

-

?

D-xylulose 5-phosphate + formaldehyde

D-glyceraldehyde 3-phosphate + glycerone

[Candida] boidinii

-

-

758071

-

-

ir

D-xylulose 5-phosphate + formaldehyde

D-glyceraldehyde 3-phosphate + glycerone

[Candida] boidinii

O93884

-

756845, 756919

-

-

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

Ogataea angusta

-

-

486053, 486056

-

-

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

Ogataea angusta

-

-

486048

i.e. 1,3-dihydroxy-2-propanone

486048

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

Ogataea angusta

-

-

486049

i.e. 1,3-dihydroxy-2-propanone

486049

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

Ogataea angusta

-

first step in formaldehyde assimilation via xylulose monophosphate (dihydroxyacetone) cycle

486048

i.e. 1,3-dihydroxy-2-propanone

486048

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

Ogataea angusta DL-1

-

-

486048

i.e. 1,3-dihydroxy-2-propanone

486048

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

Ogataea angusta DL-1

-

first step in formaldehyde assimilation via xylulose monophosphate (dihydroxyacetone) cycle

486048

i.e. 1,3-dihydroxy-2-propanone

486048

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

Ogataea angusta DL-1

-

-

486049

i.e. 1,3-dihydroxy-2-propanone

486049

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

-

486053, 486054, 486055

-

-

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

-

486046

i.e. 1,3-dihydroxy-2-propanone

486046

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

-

486048

i.e. 1,3-dihydroxy-2-propanone

486048

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

-

486049

i.e. 1,3-dihydroxy-2-propanone

486049

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

-

486051

i.e. 1,3-dihydroxy-2-propanone

486051

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

-

486052

i.e. 1,3-dihydroxy-2-propanone

486052

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

-

486050

i.e. 1,3-dihydroxy-2-propanone

486050

ir

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

-

486047

i.e. 1,3-dihydroxy-2-propanone

486047

r

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

best substrate

486051

i.e. 1,3-dihydroxy-2-propanone

486051

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

D-xylulose 5-phosphate cannot be replaced by D-ribulose 5-phosphate, D-glucose 6-phosphate, or D-ribose 5-phosphate

486051

i.e. 1,3-dihydroxy-2-propanone

486051

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

formaldehyde is the only acceptor

486050

i.e. 1,3-dihydroxy-2-propanone

486050

ir

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

no acceptors are glyceraldehyde, glyceraldehyde 3-phosphate, erythrose 4-phosphate, ribose 5-phosphate, glucose 6-phosphate, D-ribose, glutaraldehyde, dihydroxyacetone

486051

i.e. 1,3-dihydroxy-2-propanone

486051

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

no acceptors are glyceraldehyde, glyceraldehyde 3-phosphate, erythrose 4-phosphate, ribose 5-phosphate, glucose 6-phosphate, D-ribose, glutaraldehyde, dihydroxyacetone

486050

i.e. 1,3-dihydroxy-2-propanone

486050

ir

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

inducible

486052

i.e. 1,3-dihydroxy-2-propanone

486052

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

first step in formaldehyde assimilation via xylulose monophosphate (dihydroxyacetone) cycle

486048

i.e. 1,3-dihydroxy-2-propanone

486048

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii

-

pathway for formaldehyde fixation

486047

i.e. 1,3-dihydroxy-2-propanone

486047

r

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii KD1

-

-

486048

i.e. 1,3-dihydroxy-2-propanone

486048

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii KD1

-

first step in formaldehyde assimilation via xylulose monophosphate (dihydroxyacetone) cycle

486048

i.e. 1,3-dihydroxy-2-propanone

486048

?

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii KD1

-

-

486050

i.e. 1,3-dihydroxy-2-propanone

486050

ir

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii KD1

-

formaldehyde is the only acceptor

486050

i.e. 1,3-dihydroxy-2-propanone

486050

ir

D-xylulose 5-phosphate + formaldehyde

glyceraldehyde 3-phosphate + dihydroxyacetone

[Candida] boidinii KD1

-

no acceptors are glyceraldehyde, glyceraldehyde 3-phosphate, erythrose 4-phosphate, ribose 5-phosphate, glucose 6-phosphate, D-ribose, glutaraldehyde, dihydroxyacetone

486050

i.e. 1,3-dihydroxy-2-propanone

486050

ir

D-xylulose 5-phosphate + glycolaldehyde

glyceraldehyde 3-phosphate + 1,3,5-trihydroxypentane-2-one

[Candida] boidinii

-

-

486048, 486051

-

-

?

D-xylulose 5-phosphate + glycolaldehyde

glyceraldehyde 3-phosphate + 1,3,5-trihydroxypentane-2-one

[Candida] boidinii KD1

-

-

486048

-

-

?

D-xylulose 5-phosphate + ribose 5-phosphate

glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate

[Candida] boidinii

-

-

486048

-

-

?

D-xylulose 5-phosphate + ribose 5-phosphate

glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate

[Candida] boidinii KD1

-

-

486048

-

-

?

fructose 6-phosphate + formaldehyde

dihydroxyacetone + erythrose 4-phosphate

Acinetobacter sp.

-

-

486057

-

-

?

fructose 6-phosphate + formaldehyde

dihydroxyacetone + erythrose 4-phosphate

Ogataea angusta

-

-

486048, 486049

-

-

?

fructose 6-phosphate + formaldehyde

dihydroxyacetone + erythrose 4-phosphate

Ogataea angusta DL-1

-

-

486048, 486049

-

-

?

fructose 6-phosphate + formaldehyde

dihydroxyacetone + erythrose 4-phosphate

[Candida] boidinii

-

-

486048, 486049, 486050

-

-

?

fructose 6-phosphate + formaldehyde

dihydroxyacetone + erythrose 4-phosphate

[Candida] boidinii

-

fructose 6-phosphate can replace D-xylulose 5-phosphate with 10% efficiency as glycolaldehyde donor

486051

-

-

?

fructose 6-phosphate + formaldehyde

dihydroxyacetone + erythrose 4-phosphate

[Candida] boidinii KD1

-

-

486050

-

-

?

hydroxypyruvate + formaldehyde

CO2 + dihydroxyacetone

Acinetobacter sp.

-

-

486057

-

-

?

hydroxypyruvate + formaldehyde

CO2 + dihydroxyacetone

[Candida] boidinii

-

-

486048

-

-

?

hydroxypyruvate + formaldehyde

CO2 + dihydroxyacetone

[Candida] boidinii

-

hydroxypyruvate can replace D-xylulose 5-phosphate with 41.4%, hydroxypyruvate can replace D-xylulose 5-phosphate with 56%

486051

-

-

?

hydroxypyruvate + formaldehyde

CO2 + dihydroxyacetone

[Candida] boidinii

-

hydroxypyruvate can replace D-xylulose 5-phosphate with 35%

486046

-

-

?

hydroxypyruvate + formaldehyde

CO2 + dihydroxyacetone

[Candida] boidinii

-

efficiency as glycolaldehyde donor

486047

-

-

?

sedoheptulose 7-phosphate + formaldehyde

dihydroxyacetone + ribose

[Candida] boidinii

-

-

486048, 486050

-

-

?

sedoheptulose 7-phosphate + formaldehyde

dihydroxyacetone + ribose

[Candida] boidinii

-

sedoheptulose 7-phosphate can replace D-xylulose 5-phosphate with 10% efficiency as glycolaldehyde donor

486051

-

-

?

sedoheptulose 7-phosphate + formaldehyde

dihydroxyacetone + ribose

[Candida] boidinii KD1

-

-

486050

-

-

?

additional information

?

-

Mycobacterium sp.

Q9ALQ6

dihydroxyacetone synthase (DHAS) is a key enzyme involved in the assimilation of methanol in Mycobacterium sp. strain JC1 DSM 3803. The gene is transcribed only in cells growing on methanol. The expression of dasS in Mycobacterium sp. strain JC1 is free from catabolite repression

688869

-

-

?

additional information

?

-

Mycobacterium sp. DSM 3803 / JC1

Q9ALQ6

dihydroxyacetone synthase (DHAS) is a key enzyme involved in the assimilation of methanol in Mycobacterium sp. strain JC1 DSM 3803. The gene is transcribed only in cells growing on methanol. The expression of dasS in Mycobacterium sp. strain JC1 is free from catabolite repression

688869

-

-

?

additional information

?

-

[Candida] boidinii

-

with xylulose 5-phosphate as glycolyl donor: aliphatic aldehydes (C1-C7), glycolaldehyde and glyceraldehyde are better acceptors than ribose 5-phosphate

486047

-

-

?