2.2.1.8: fluorothreonine transaldolase

This is an abbreviated version!
For detailed information about fluorothreonine transaldolase, go to the full flat file.

Reaction

Synonyms

4-fluorothreoinine transaldolase, 4-fluorothreonine transaldolase, 4-FTase, FTase

ECTree

2 Transferases

2.2 Transferring aldehyde or ketonic groups

2.2.1 Transketolases and transaldolases

2.2.1.8 fluorothreonine transaldolase

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Results	in table
37	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
5	Cofactor
3	General Information
8	kcat/KM [mM/s]
8	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
12	Organism
1	Pathway
3	Purification (Commentary)
1	Reaction
1	Reaction Type
8	Reference
22	Substrates and Products (Substrate)
3	Subunits
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
8	Turnover Number [1/s]

Reference

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Reference on EC 2.2.1.8 - fluorothreonine transaldolase

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636461

Murphy, C.D.; Schaffrath, C.; O'Hagan, D.

Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya

Chemosphere

455-461

2003

Streptomyces cattleya, Streptomyces cattleya NRRL 8057

12738270

639494

Murphy, C.D.; O'Hagan, D.; Schaffrath, C.

Identification of a PLP-dependent threonine transaldolase: a novel enzyme involved in 4-fluorothreonine biosynthesis in Streptomyces cattleya

Angew. Chem.

4479-4481

2001

Streptomyces cattleya, Streptomyces cattleya NRRL 8057

12404452

703173

Deng, H.; Cross, S.M.; McGlinchey, R.P.; Hamilton, J.T.; OHagan, D.

In vitro reconstituted biotransformation of 4-fluorothreonine from fluoride ion: application of the fluorinase

Chem. Biol.

1268-1276

2008

Streptomyces cattleya (B6VP39)

19101471

719042

Zhao, C.; Li, P.; Deng, Z.; Ou, H.Y.; McGlinchey, R.P.; OHagan, D.

Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants

Bioorg. Chem.

1-7

2012

Streptomyces cattleya (F8JMF0), Streptomyces cattleya DSM 46488 (F8JMF0)

22858315

755884

Wu, L.; Tong, M.H.; Raab, A.; Fang, Q.; Wang, S.; Kyeremeh, K.; Yu, Y.; Deng, H.

An unusual metal-bound 4-fluorothreonine transaldolase from Streptomyces sp. MA37 catalyses promiscuous transaldol reactions

Appl. Microbiol. Biotechnol.

104

3885-3896

2020

Streptomyces sp. MA37

32140842