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2.3.1.105: alkylglycerophosphate 2-O-acetyltransferase

This is an abbreviated version!
For detailed information about alkylglycerophosphate 2-O-acetyltransferase, go to the full flat file.

Reaction

acetyl-CoA
+
1-alkyl-sn-glycero-3-phosphate
=
CoA
+
1-Alkyl-2-acetyl-sn-glycero-3-phosphate

Synonyms

1-O-alkyl-sn-glycero-3-phosphate:acetyl-CoA acetyltransferase, alkyllyso-GP:acetyl-CoA acetyltransferase, ALPA AT

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.105 alkylglycerophosphate 2-O-acetyltransferase

Inhibitors

Inhibitors on EC 2.3.1.105 - alkylglycerophosphate 2-O-acetyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ADP
-
29% decline in subcellular fraction P3A activity, 43% decline in subcellular fraction P3B activity and 7% decline in subcellular fraction P3D activity
Alkaline phosphatase
-
92-95% activity lost for subcellular fractions P3A and P3B
-
ATP
-
little effect on the enzyme activity for the subcellular fraction P3A, 55-64% decline in the subcellular fraction P3B
CaCl2
-
1 mM CaCl2 inhibits 73% and 24% activity of subcellular fractions P3B and P3D respectively
dithiothreitol
-
-
EDTA
-
inhibits 30% fraction P3D, does not inhibit subcellular fraction P3A
MgADP-
-
inhibitory effects less severe than MgATP
MgAMP
-
less inhibitory effect than MgADP
MgATP2-
-
extreme inhibition in all microsomal fractions
MgCl2
-
at 2 mM: 30, 28 and 58% inhibition of subcellular fractions P3A, P3B and P3D activities respectively
Sodium vanadate
-
inhibits at concentrations above 0.025 mM
additional information
-