2.3.1.108: alpha-tubulin N-acetyltransferase

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For detailed information about alpha-tubulin N-acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyl-CoA:alpha-tubulin-L-lysine Ne-acetyltransferase, alpha-TAT, alpha-tubulin acetylase, alpha-tubulin acetyltransferase, alpha-tubulin K40 acetyltransferase, alpha-tubulin N-acetyltransferase 1, alphaTAT, alphaTAT1, alphaTAT2, ATAT-2, ATAT1, ATAT1 acetylase, ATAT1 tubulin acetyltransferase, elongator, KAT, lysine acetyltransferase, Mec-17, TAT, tubulin acetyltransferase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.108 alpha-tubulin N-acetyltransferase

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Results	in table
1	Activating Compound
1631	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
11	Cofactor
3	Crystallization (Commentary)
303	Disease/ Diagnostics
1	Expression
47	General Information
5	Inhibitors
20	kcat/KM [mM/s]
1	Ki Value [mM]
22	KM Value [mM]
22	Localization
6	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
40	Organism
18	PDB ID
5	pH Optimum
2	Posttranslational Modification
44	Protein Variants
3	Purification (Commentary)
1	Reaction
1	Reaction Type
39	Reference
36	Source Tissue
42	Substrates and Products (Substrate)
3	Subunits
53	Synonyms
1	Systematic Name
20	Turnover Number [1/s]

Posttranslational Modification

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Posttranslational Modification on EC 2.3.1.108 - alpha-tubulin N-acetyltransferase

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POSTTRANSLATIONAL MODIFICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

acetylation

Mus musculus

Q8K341

enzyme catalyzes acetylation of multiple lysine residues on itself. Autoacetylation of alphaTAT1 increases its catalytic activity at microtubules

736795

acylation

Bombyx mori

H9IXT4

enzyme can be acylated at residue K156

755907