2.3.1.12: dihydrolipoyllysine-residue acetyltransferase

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For detailed information about dihydrolipoyllysine-residue acetyltransferase, go to the full flat file.

Reaction

Synonyms

acetyltransferase, lipoate, DHLTA, dihydrolipoamide acetyltransferase, dihydrolipoate acetyltransferase, dihydrolipoic transacetylase, dihydrolipoyl acetyl transferase, dihydrolipoyl acetyltransferase, dihydrolipoyl acetyltransferase component E2, dihydrolipoyl acetyltransferase E2p, dihydrolipoyl transacetylase, dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, DLAT, E2, E2p, hE2, Lat1, lipoate acetyltransferase, lipoate transacetylase, lipoic acetyltransferase, lipoic acid acetyltransferase, lipoic transacetylase, lipoylacetyltransferase, More, myelin-proteolipid O-palmitoyltransferase, palmitoyl-CoA:myelin-proteolipid O-palmitoyltransferase, pyruvate dehydrogenase complex component E2, pyruvate dehydrogenase complex component E2p, pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase component, thioltransacetylase A, transacetylase X

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.12 dihydrolipoyllysine-residue acetyltransferase

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Results	in table
20867	AA Sequence
2	Application
1	CAS Registry Number
35	Cloned(Commentary)
1	Cofactor
8	Crystallization (Commentary)
84	Disease/ Diagnostics
6	General Information
3	General Stability
10	Inhibitors
20	KM Value [mM]
18	Localization
7	Metals/Ions
95	Molecular Weight [Da]
93	Natural Substrates/ Products (Substrates)
108	Organism
10	Pathway
269	PDB ID
4	pH Optimum
2	pH Stability
19	Posttranslational Modification
62	Protein Variants
62	Purification (Commentary)
3	Reaction
1	Reaction Type
107	Reference
13	Renatured (Commentary)
37	Source Tissue
17	Specific Activity [micromol/min/mg]
2	Storage Stability
100	Substrates and Products (Substrate)
60	Subunits
63	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
5	Temperature Stability [°C]
4	Turnover Number [1/s]

Application

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Application on EC 2.3.1.12 - dihydrolipoyllysine-residue acetyltransferase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

degradation

Chlorella sp. MM3

-

strain MM3 can grow on up to 250 microM pyrene in culture medium. With an initial cell density of 30000000 cells/ml, nearly 70% of 50 microM pyrene is degraded after 7 days of incubation. Nearly 20% increase in degradation of pyrene is observed with the use of 0.005% Tween 80. Dihydrolipoamide acetyltransferase accumulates during microalgal degradation of pyrene. The microalgal cells immobilized in calcium alginate completely degrade 50 microM of pyrene within 10 days in nonsterile soil slurry treated with 0.005% Tween 80

755757

molecular biology

Saccharomyces cerevisiae

A6ZS09

dihydrolipoamide acetyltransferase is shown to be a metabolic longevity factor and is required for calorie restriction-mediated life span extension

674890