2.3.1.122: trehalose O-mycolyltransferase

This is an abbreviated version!
For detailed information about trehalose O-mycolyltransferase, go to the full flat file.

Word Map on EC 2.3.1.122

2.3.1.122

tuberculosis

mycobacterium

bovis

esat-6

antigen-specific

ifn-gamma

bacille

ankara

prime-boost

mva85a

immunodominant

mycolylation

bcg-vaccinated

mycolic

tuberculin

booster

polyfunctional

aerosol

bcg-primed

calmette-guerin

elispot

drug development

th1-type

fibronectin-binding

bcg-induced

medicine

tuberculosis-infected

biotechnology

dimycolate

post-vaccination

ifn-gamma-producing

Reaction

2 alpha,alpha-trehalose 6-mycolate =

Synonyms

Ag85A, ag85C, alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase, antigen 85A, antigen 85C, cg0413, CMT1, corynomycoloyl transferase C, FbpA mycolyltransferase, mycoloyl transferase, mycolyl-transferase Ag85A, mycolyltransferase, mycolyltransferase, trehalose 6-monomycolate-trehalose, MytC

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.122 trehalose O-mycolyltransferase

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Results	in table
2530	AA Sequence
3	Application
1	CAS Registry Number
8	Cloned(Commentary)
1	Cofactor
5	Crystallization (Commentary)
9	General Information
3	General Stability
20	IC50 Value
40	Inhibitors
4	KM Value [mM]
4	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
27	Organism
2	Pathway
19	PDB ID
7	pH Optimum
1	pH Range
9	Protein Variants
7	Purification (Commentary)
6	Reaction
1	Reaction Type
24	Reference
3	Specific Activity [micromol/min/mg]
26	Substrates and Products (Substrate)
2	Subunits
38	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.3.1.122 - trehalose O-mycolyltransferase

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2 alpha,alpha-trehalose 6-mycolate

alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate

2 entries

alpha,alpha-trehalose 6-mycolate

alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate

3 entries

alpha,alpha-trehalose 6-mycolate + alpha,alpha-trehalose

alpha,alpha-trehalose + alpha,alpha-trehalose 6-mycolate

Mycolicibacterium smegmatis

486242

additional information

Mycobacterium tuberculosis variant bovis

the enzyme, in form of DNA and protein or peptide fragments, is immunogenic in C57BL/6 mice and effective as tuberculosis vaccine against Mycobacterium tuberculosis strain H37Rv, alone and especially in combination with PstS3 DNA and/or protein, detailed overview

673960