2.3.1.13: glycine N-acyltransferase
This is an abbreviated version!
For detailed information about glycine N-acyltransferase, go to the full flat file.
Reaction
Synonyms
acyltransferase, glycine, GlyAT, GLYATL1, GLYATL2, GLYATL3, glycine acyltransferase, glycine N-acyltransferase, glycine N-acyltransferase-like 3, glycine-N-acylase, glycine-N-acyltransferase, glycine-N-acyltransferase like 1
ECTree
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Reaction
Reaction on EC 2.3.1.13 - glycine N-acyltransferase
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sequential reaction mechanism, acyl-CoA substrate adds to the enzyme first, glycine adds before CoA leaves and the peptide product dissociates last
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acyl-CoA + glycine = CoA + N-acylglycine
residue Glu226 functions to deprotonate glycine, facilitating nucleophilic attack on the acyl-CoA substrate