2.3.1.137: carnitine O-octanoyltransferase

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For detailed information about carnitine O-octanoyltransferase, go to the full flat file.

Reaction

Synonyms

carnitine acyltransferase, Carnitine medium-chain acyltransferase, carnitine octanoyltransferase, COT, CRAT, CrOT, easily solubilized mitochondrial carnitine palmitoyltransferase, medium-chain carnitine acyltransferase, medium-chain/long-chain carnitine acyltransferase, More, overt mitochondrial carnitine palmitoyltransferase, short-chain carnitine acyltransferase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.137 carnitine O-octanoyltransferase

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Results	in table
1	Activating Compound
21	AA Sequence
1	CAS Registry Number
8	Cloned(Commentary)
1	Crystallization (Commentary)
42	Disease/ Diagnostics
1	General Information
2	General Stability
35	Inhibitors
5	Ki Value [mM]
63	KM Value [mM]
84	Localization
13	Molecular Weight [Da]
131	Natural Substrates/ Products (Substrates)
563	Organism
8	PDB ID
3	pH Optimum
2	pH Range
9	Protein Variants
14	Purification (Commentary)
4	Reaction
3	Reaction Type
64	Reference
75	Source Tissue
3	Specific Activity [micromol/min/mg]
6	Storage Stability
304	Substrates and Products (Substrate)
9	Subunits
46	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

General Stability

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General Stability on EC 2.3.1.137 - carnitine O-octanoyltransferase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

quite unstable, labile in Triton X-100 and octylglucoside, stable in 8 mM CHAPS, 200 mM guanidium chloride and 0.5% Tween 20

Rattus norvegicus

-

486298

stable for at least 1 week in 100 mM phosphate buffer with 0.4 M KCl, pH 5.5-7.5

Rattus norvegicus

-

486292