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2.3.1.156: phloroisovalerophenone synthase

This is an abbreviated version!
For detailed information about phloroisovalerophenone synthase, go to the full flat file.

Word Map on EC 2.3.1.156

Reaction

isobutyryl-CoA
+ 3 malonyl-CoA = 4 CoA + 3 CO2 +
phlorisobutyrophenone

Synonyms

3-methyl-1-(trihydroxyphenyl)butan-1-one synthase, bifunctional chalcone/(iso)valerophenone synthase, CHS2-1, phlorisovalerophenone synthase, valerophenone synthase, VPS

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.156 phloroisovalerophenone synthase

Application

Application on EC 2.3.1.156 - phloroisovalerophenone synthase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
brewing
B3GEA8, B3GEA9, B3GEB0, B3GEB1, B3GEB2, B3GEB3, B3GEB4, B3GEB5, B3GEB6, O80400
valerophenone synthase is a key gene in the bitter acid biosynthesis of hop, sequence analysis reveals nine single nucleotide polymorphisms in VPS,understanding variation in the genes of the bitter acid biosynthetic pathway is required to improve the content and quality of bitter acids in hop, real-time quantitative reverse-transcription polymerase chain reaction analysis shows a clear link between VPS expression and bitter acid content
nutrition
-
cones of the hop plant used in the beer-brewing process
synthesis
-
total enzymatic synthesis of acylphloroglucinol glucosides is achieved by co-incubation of recombinant dual functional chalcone/valerophenone synthase and UGT71K3 proteins with essential coenzyme A esters and UDP-glucose. Proteins UGT71K3a/b catalyze the glucosylation of diverse hydroxycoumarins, naphthols and flavonoids, enzymatically synthesized acylphloroglucinol aglycones and pelargonidin