2.3.1.156: phloroisovalerophenone synthase
This is an abbreviated version!
For detailed information about phloroisovalerophenone synthase, go to the full flat file.
Word Map on EC 2.3.1.156
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2.3.1.156
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humulus
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brewing
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bitter
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flavonoid
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beer
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lupulin
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polyketide
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chs_h1
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synthases
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glandular
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stilbene
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cannabis
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benthamiana
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xanthohumol
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flavor
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isobutyryl-coa
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prenyltransferase
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2.3.1.74
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hybrida
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cannabinoids
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phloroglucinols
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olivetolic
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nutrition
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synthesis
- 2.3.1.156
-
humulus
- brewing
-
bitter
- flavonoid
-
beer
-
lupulin
- polyketide
- chs_h1
- synthases
- glandular
- stilbene
- cannabis
- benthamiana
- xanthohumol
-
flavor
- isobutyryl-coa
- prenyltransferase
-
2.3.1.74
- hybrida
- cannabinoids
- phloroglucinols
-
olivetolic
- nutrition
- synthesis
Reaction
Synonyms
3-methyl-1-(trihydroxyphenyl)butan-1-one synthase, bifunctional chalcone/(iso)valerophenone synthase, CHS2-1, phlorisovalerophenone synthase, valerophenone synthase, VPS
ECTree
2.3.1.156 phloroisovalerophenone synthaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.3.1.156 - phloroisovalerophenone synthase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
isovaleryl-CoA + 3 malonyl-CoA
phloroisovalerophenone + 3 CO2 + 4 CoA
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isovaleryl-CoA is the preferred starter substrate of isoform CHS2-1
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?
isobutyryl-CoA + 3 malonyl-CoA
phloroisobutyrophenone + 3 CO2 + 4 CoA
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-
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?
isobutyryl-CoA + 3 malonyl-CoA
phloroisobutyrophenone + 3 CO2 + 4 CoA
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-
-
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?
isobutyryl-CoA + 3 malonyl-CoA
phloroisobutyrophenone + 3 CO2 + 4 CoA
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-
phloroglucinol derivative, intermediates in the biosynthesis of the hop bitter alpha- and beta-acids
?
isobutyryl-CoA + 3 malonyl-CoA
phloroisobutyrophenone + 3 CO2 + 4 CoA
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?
isobutyryl-CoA + 3 malonyl-CoA
phloroisobutyrophenone + 3 CO2 + 4 CoA
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enzyme is involved in formation of the hyperforin skeleton of Hypericum calycinum
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-
?
isovaleryl-CoA + malonyl-CoA
phloroisovalerophenone + CO2 + CoA
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?
isovaleryl-CoA + malonyl-CoA
phloroisovalerophenone + CO2 + CoA
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phloroglucinol derivative, intermediates in the biosynthesis of the hop bitter alpha- and beta-acids
?
additional information
?
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the Fragaria vesca bifunctional chalcone synthase enzymes readily catalyze the condensation isovaleryl-Coenzyme A (CoA) and isobutyryl-CoA, with three molecules of malonyl-CoA to form phlorisovalerophenone and phlorisobutyrophenone, respectively, and form naringenin chalcone when 4-coumaroyl-CoA is used as starter molecule
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?
additional information
?
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the enzyme is responsible for the biosynthesis of the precursors of alpha-acid and beta-acid
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?
