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2.3.1.161: lovastatin nonaketide synthase

This is an abbreviated version!
For detailed information about lovastatin nonaketide synthase, go to the full flat file.

Word Map on EC 2.3.1.161

Reaction

9 malonyl-CoA + 11 NADPH + 10 H+ +

S-adenosyl-L-methionine
+
holo-[lovastatin nonaketide synthase]
=
dihydromonacolin L-[lovastatin nonaketide synthase]
+ 9 CoA + 9 CO2 + 11 NADP+ +
S-adenosyl-L-homocysteine
+ 6 H2O

Synonyms

LNKS, lovastatin nonaketide synthase, LovB, synthase, lovastatin nonaketide

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.161 lovastatin nonaketide synthase

KCat KM Value

KCat KM Value on EC 2.3.1.161 - lovastatin nonaketide synthase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
18.93
(4E,6E)-3-oxoocta-4,6-dienoyl-N-acetylcysteamine
pH not specified in the publication, temperature not specified in the publication
0.31
3-oxohexanoyl-N-acetylcysteamine
pH not specified in the publication, temperature not specified in the publication
0.06
3-oxooctanoyl-N-acetylcysteamine
pH not specified in the publication, temperature not specified in the publication