2.3.1.168: dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
This is an abbreviated version!
For detailed information about dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, go to the full flat file.
Word Map on EC 2.3.1.168
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2.3.1.168
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branched-chain
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bcaas
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merits
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protein-restricted
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retinal
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urine
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metformin
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women
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maple
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l-glutamate
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syrup
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agriculture
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synthesis
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medicine
- 2.3.1.168
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branched-chain
-
bcaas
-
merits
-
protein-restricted
- retinal
- urine
- metformin
- women
-
maple
- l-glutamate
- syrup
- agriculture
- synthesis
- medicine
Reaction
Synonyms
Bkd, BKDH, DBT, dihydrolipoamide branched chain transacylase, dihydrolipoyl transacetylase, DLD, E2, E2p, More
ECTree
2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.3.1.168 - dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-methylpropanoyl-CoA + dihydrolipoamide
CoA + S-2-methylpropanoyldihydrolipoamide
-
-
identification by mass spectrometry
r
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
2-oxoglutaryl-CoA + dihydrolipoamide
CoA + S-(2-oxoglutaryl)dihydrolipoamide
low activity
-
-
?
3-methylisovaleryl-CoA + dihydrolipoamide
CoA + S-(3-methylisovaleryl)dihydrolipoamide
-
-
-
?
4-methylthiobutyryl-CoA + dihydrolipoamide
CoA + S-(4-methylthiobutyryl)dihydrolipoamide
low activity
-
-
?
butyryl-CoA + dihydrolipoamide
CoA + S-butyryldihydrolipoamide
-
-
-
?
isobutyryl-CoA + dihydrolipoamide
CoA + S-isobutyryldihydrolipoamide
-
-
-
r
isocaproyl-CoA + dihydrolipoamide
CoA + S-isohexanoyldihydrolipoamide
-
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
-
r
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
recombinant apo-E2 devoid of lipoic acid is fully active
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
enzyme contains 1 lipoyl residue per E2 chain of branched-chain 2-oxo acid dehydrogenase
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
multienzyme complex, scheme of the reaction steps
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
enzyme contains 1 lipoyl residue per E2 chain of branched-chain 2-oxo acid dehydrogenase
-
?
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine
CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
-
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 3 lipoyl residues per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 3 lipoyl residues per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
low activity
-
r
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 3 lipoyl residues per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 2 lipoyl residues per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 3 lipoyl residues per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 3 lipoyl residues per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 2 lipoyl residues per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 3 lipoyl residues per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 1 lipoyl residue per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
enzyme contains 1 lipoyl residue per E2 chain of pyruvate dehydrogenase complex
-
?
acetyl-CoA + dihydrolipoamide
CoA + S-acetyldihydrolipoamide
-
part of the pyruvate dehydrogenase reaction
-
?
isovaleryl-CoA + dihydrolipoamide
CoA + S-isovaleryldihydrolipoamide
-
-
-
r
isovaleryl-CoA + dihydrolipoamide
CoA + S-isovaleryldihydrolipoamide
-
recombinant enzyme, i.e. E2 domain, overexpressed in Escherichia coli
-
-
r
isovaleryl-CoA + dihydrolipoamide
CoA + S-isovaleryldihydrolipoamide
-
-
-
?
additional information
?
-
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enzyme is a mitochondrial autoantigen, epitope mapping is performed to define the recognition sites by sera and T cells of patients suffering idopathic dilated cardiomyopathy and dilated cardiomyopathy
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-
?
