2.3.1.169: CO-methylating acetyl-CoA synthase

This is an abbreviated version!
For detailed information about CO-methylating acetyl-CoA synthase, go to the full flat file.

Reaction

Synonyms

ACDS multienzyme complex, acetyl-CoA decarbonylase/synthase multienzyme complex, acetyl-CoA decarboxylase/synthase, Acetyl-CoA synthase, Acetyl-coenzyme A synthase, acetyl-coenzyme A synthase/carbon monoxide dehydrogenase, ACS/CODH, ACSCh, Carbon monoxide dehydrogenase, carbon monoxide dehydrogenase-corrinoid enzyme complex, carbon monoxide dehydrogenase/acetyl coenzyme A synthase, carbon monoxide dehydrogenase/acetyl-CoA synthase, carbon monoxide dehydrogenase/acetyl-coenzyme A synthase, CDH1, Cdh2, CO dehydrogenase, CO dehydrogenase enzyme complex, CO dehydrogenase/acetyl CoA synthase, CO dehydrogenase/acetyl coenzyme A synthase, CO dehydrogenase/acetyl-CoA synthase, CODH, CODH/ACS, CODH/ASC, KSU1_D0226, KSU1_D0227, monoxide dehydrogenase/acetyl-CoA synthase, multienzyme carbon monoxide dehydrogenase complex, multienzyme CO dehydrogenase/acetyl-CoA synthase complex

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.169 CO-methylating acetyl-CoA synthase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
5	Activating Compound
2659	AA Sequence
2	CAS Registry Number
8	Cloned(Commentary)
3	Cofactor
6	Crystallization (Commentary)
1	Expression
23	General Information
2	General Stability
21	Inhibitors
1	kcat/KM [mM/s]
2	Ki Value [mM]
11	KM Value [mM]
1	Localization
62	Metals/Ions
11	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
60	Organism
7	Pathway
48	PDB ID
13	pH Optimum
11	Protein Variants
7	Purification (Commentary)
32	Reaction
1	Reaction Type
47	Reference
1	Renatured (Commentary)
1	Source Tissue
7	Specific Activity [micromol/min/mg]
66	Substrates and Products (Substrate)
13	Subunits
42	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
5	Turnover Number [1/s]

Natural Substrates Products

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Natural Substrates Products on EC 2.3.1.169 - CO-methylating acetyl-CoA synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Natural Substrate Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

acetyl-CoA + corrinoid protein

CoA + CO + methylcorrinoid protein

5 entries

additional information

?

-

11 entries

acetyl-CoA + corrinoid protein

CoA + CO + methylcorrinoid protein

Carboxydothermus hydrogenoformans

-

-

719862, 720372

-

-

r

acetyl-CoA + corrinoid protein

CoA + CO + methylcorrinoid protein

Carboxydothermus hydrogenoformans DSM 6008

-

-

719862

-

-

r

acetyl-CoA + corrinoid protein

CoA + CO + methylcorrinoid protein

Methanosarcina thermophila

-

-

719862

-

-

r

acetyl-CoA + corrinoid protein

CoA + CO + methylcorrinoid protein

Methanosarcina thermophila TM-1

-

-

719862

-

-

r

acetyl-CoA + corrinoid protein

CoA + CO + methylcorrinoid protein

Moorella thermoacetica

-

-

714240

-

-

?

additional information

?

-

Methanosarcina barkeri

-

the bifuctional enzyme CO dehydrogenase/acetyl-CoA synthase is central to the Wood-Ljungdahl pathway of autotrophic CO2 fixation

644864

-

-

?

additional information

?

-

Moorella thermoacetica

-

key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway

390475

-

-

?

additional information

?

-

Moorella thermoacetica

-

key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway

644678

-

-

?

additional information

?

-

Moorella thermoacetica

-

key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway

644850

-

-

?

additional information

?

-

Moorella thermoacetica

-

key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway

644851

-

-

?

additional information

?

-

Moorella thermoacetica

-

key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway

644855

-

-

?

additional information

?

-

Moorella thermoacetica

-

key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway

644857

-

-

?

additional information

?

-

Moorella thermoacetica

-

key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway

644861

-

-

?

additional information

?

-

Moorella thermoacetica

-

enzyme and a corrinoid/iron-sulfur protein, methyltransferase and an electron transfer protein such as ferredoxin II play a pivotal role in the conversion of methylhydrofolate, CO, and CoA to acetyl-CoA

644674

-

-

?

additional information

?

-

Moorella thermoacetica

-

the bifuctional enzyme CO dehydrogenase/acetyl-CoA synthase is central to the Wood-Ljungdahl pathway of autotrophic CO2 fixation

644864

-

-

?

additional information

?

-

Moorella thermoacetica

-

the purified carbon monoxide dehydrogenase, EC 1.2.7.4, from Clostridium thermoaceticum is the only protein required to catalyze a reversible exchange reaction between carbon monoxide and the carbonyl group of acetyl-CoA. Carbon dioxide also exchanges with the C-1 of acetyl-coA, but at a much lower rate than does CO

390459

-

-

?