2.3.1.171: anthocyanin 6''-O-malonyltransferase

This is an abbreviated version!
For detailed information about anthocyanin 6''-O-malonyltransferase, go to the full flat file.

Reaction

Synonyms

3MaT, AAT1, anthocyanidin 3-glucoside malonyltransferase, anthocyanidin 3-O-glucoside 6''-O-acyltransferase-like, anthocyanidin malonyltransferase, anthocyanin 3-glucoside malonyltransferase, anthocyanin acyltransferase 1, anthocyanin malonyltransferase, Dm3MaT1, Dv3MaT, malonyl-CoA: anthocyanidin 3-O-glucoside-6''-O-malonyltransferase, malonyl-CoA:anthocyanin 3-O-glucoside-6'�-O-malonyltransferase, malonyl-coenzyme A:anthocyanidin 3-O-glucoside 6''-O-malonyltransferase, malonyl-coenzyme A:anthocyanidin 3-O-glucoside-6"-O-malonyltransferase, malonyl-coenzyme A:anthocyanidin malonyltransferase, malonyl-coenzyme A:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase, malonyltransferase, anthocyanidin 3-glucoside, protein GRMZM2G387394, Sc3MaT

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.171 anthocyanin 6''-O-malonyltransferase

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Results	in table
7	AA Sequence
2	Application
1	CAS Registry Number
4	Cloned(Commentary)
1	General Information
28	Inhibitors
6	KM Value [mM]
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
9	Organism
4	Pathway
5	pH Optimum
2	pH Range
1	pH Stability
11	Protein Variants
1	Purification (Commentary)
1	Reaction
9	Reference
6	Source Tissue
1	Storage Stability
38	Substrates and Products (Substrate)
1	Subunits
23	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
13	Turnover Number [1/s]

Engineering

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Engineering on EC 2.3.1.171 - anthocyanin 6''-O-malonyltransferase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

A38P

Chrysanthemum x morifolium

-

mutant in 3-O-glucoside-6’’-malonyltransferase containing regions A and C of anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase, threefold decrease in 3-O-glucoside-6’’-malonyltransferase activity, anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase activity is 50% of 3-O-glucoside-3’’,6’’-dimalonyltransferase wild-type

674809

A413T

Chrysanthemum x morifolium

-

mutant in 3-O-glucoside-6’’-malonyltransferase containing regions A and C of anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase, fivefold decrease in 3-O-glucoside-6’’-malonyltransferase activity, anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase activity is 50% of 3-O-glucoside-3’’,6’’-dimalonyltransferase wild-type

674809

K419N

Chrysanthemum x morifolium

-

mutant in 3-O-glucoside-6’’-malonyltransferase containing regions A and C of anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase, 50% decrease in 3-O-glucoside-6’’-malonyltransferase activity, anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase activity is 70% of 3-O-glucoside-3’’,6’’-dimalonyltransferase wild-type

674809

L37V

Chrysanthemum x morifolium

-

mutant in 3-O-glucoside-6’’-malonyltransferase containing regions A and C of anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase, threefold decrease in 3-O-glucoside-6’’-malonyltransferase activity, anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase activity similar to 3-O-glucoside-3’’,6’’-dimalonyltransferase wild-type

674809

Q51P

Chrysanthemum x morifolium

-

mutant in 3-O-glucoside-6’’-malonyltransferase containing regions A and C of anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase, 2.5fold decrease in 3-O-glucoside-6’’-malonyltransferase activity, anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase activity is 50% of 3-O-glucoside-3’’,6’’-dimalonyltransferase wild-type

674809

T35G

Chrysanthemum x morifolium

-

mutant in 3-O-glucoside-6’’-malonyltransferase containing regions A and C of anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase, sixfold decrease in 3-O-glucoside-6’’-malonyltransferase activity, increase in anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase activity

674809

Y411N

Chrysanthemum x morifolium

-

mutant in 3-O-glucoside-6’’-malonyltransferase containing regions A and C of anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase, ninefold decrease in 3-O-glucoside-6’’-malonyltransferase activity, no anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase activity

674809

biotechnology

Dahlia pinnata

Q8GSN8

production of anthocyanins to use their anti-oxidative, anti-inflammatory, anti-cancer, anti-obesity, anti-diabetic, and cardioprotective properties

702785

medicine

Dahlia pinnata

Q8GSN8

production of anthocyanins to use their anti-oxidative, anti-inflammatory, anti-cancer, anti-obesity, anti-diabetic, and cardioprotective properties

702785

synthesis

Dahlia pinnata

Q8GSN8

production of anthocyanins to use their anti-oxidative, anti-inflammatory, anti-cancer, anti-obesity, anti-diabetic, and cardioprotective properties

702785

additional information

Chrysanthemum x morifolium

-

swapping of regions A, B and C of anthocyanidin 3-O-glucoside-6’’-malonyltransferase and anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase and identification of amino acid residues that are important for anthocyanidin 3-O-glucoside-3’’,6’’-dimalonyltransferase activity in regions A and C

674809