2.3.1.179: beta-ketoacyl-[acyl-carrier-protein] synthase II

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For detailed information about beta-ketoacyl-[acyl-carrier-protein] synthase II, go to the full flat file.

Reaction

Synonyms

3-ketoacyl acyl synthase II, 3-ketoacyl-ACP synthase, 3-ketoacyl-ACP synthase 2, 3-ketoacyl-ACP synthase II, 3-oxoacyl-(acylcarrier protein) synthase II, 3-oxoacyl-ACP synthase II, B-ketoacyl-ACP synthase II, beta-ketoacyl ACP-synthase II, beta-ketoacyl acyl carrier protein synthase II, beta-ketoacyl acyl-carrier protein synthase II, beta-ketoacyl synthase II, beta-ketoacyl-(acyl-carrier-protein) synthase II, beta-ketoacyl-ACP synthase FabF3, beta-ketoacyl-ACP synthase II, beta-ketoacyl-acyl carrier protein synthase I/II, beta-ketoacyl-acyl carrier protein synthase II, beta-ketoacyl-acyl carrier protein synthases II, beta-ketoacyl-acyl carrier protein synthetase II, beta-ketoacyl-acyl-carrier protein synthase II, beta-ketoacyl-acyl-carrier-protein synthase II, beta-ketoacyl-[ACP] synthase II, beta-ketoacyl-[ACP] synthase-II, beta-ketoacyl-[acyl carrier protein (ACP)] synthase II, beta-ketoacyl-[acyl-carrier protein (ACP)] synthase II, beta-ketoacyl-[acyl-carrier-protein] synthase II, FabB, FabB/F, FabF, FabF elongation condensing enzyme, FabF of type II fatty acid biosynthesis, FabF1, FASII, fatty acid synthesis type II, KAS II, KAS-II, KAS2, KASII

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II

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Results	in table
43692	AA Sequence
9	Application
1	CAS Registry Number
27	Cloned(Commentary)
11	Crystallization (Commentary)
1	Expression
23	General Information
1	General Stability
7	IC50 Value
70	Inhibitors
8	kcat/KM [mM/s]
23	KM Value [mM]
2	Localization
1	Metals/Ions
9	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
62	Organism
26	Pathway
44	PDB ID
5	pH Optimum
3	pI Value
27	Protein Variants
12	Purification (Commentary)
4	Reaction
1	Reaction Type
57	Reference
30	Source Tissue
3	Specific Activity [micromol/min/mg]
46	Substrates and Products (Substrate)
13	Subunits
104	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
8	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 2.3.1.179 - beta-ketoacyl-[acyl-carrier-protein] synthase II

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1

lauroyl-CoA

Escherichia coli

-

wild type protein, acceptor malonyl-CoA, 0.5 mM malonyl-CoA, pH 6.5, 25°C

718888

3.8

malonyl-ACP

Escherichia coli

-

wild type protein, donor lauroyl-ACP, 0.01 mM lauroyl-ACP, pH 6.5, 25°C

718888

0.083 - 0.83

malonyl-CoA

2 entries

0.037

malonyl-phosphopantetheine

Escherichia coli

-

wild type protein, donor lauroyl-CoA, 0.075 mM lauroyl-CoA, pH 6.5, 25°C

718888

4.2

malonyl-phosphopantetheine-14-mer

Escherichia coli

-

wild type protein, donor lauroyl-CoA, 0.075 mM lauroyl-CoA, pH 6.5, 25°C

718888

3.8

malonyl-phosphopantetheine-16-mer

Escherichia coli

-

wild type protein, donor lauroyl-CoA, 0.075 mM lauroyl-CoA, pH 6.5, 25°C

718888

0.083

malonyl-phosphopantetheine-8-mer

Escherichia coli

-

wild type protein, donor lauroyl-CoA, 0.075 mM lauroyl-CoA, pH 6.5, 25°C

718888

0.083

malonyl-CoA

Escherichia coli

-

wild type protein, donor lauroyl-CoA, 0.075 mM lauroyl-CoA, pH 6.5, 25°C

718888

0.83

malonyl-CoA

Escherichia coli

-

R206G mutant protein, donor lauroyl-CoA, 0.1 mM lauroyl-CoA, pH 6.5, 25°C

718888