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2.3.1.180: beta-ketoacyl-[acyl-carrier-protein] synthase III

This is an abbreviated version!
For detailed information about beta-ketoacyl-[acyl-carrier-protein] synthase III, go to the full flat file.

Word Map on EC 2.3.1.180

Reaction

acetyl-CoA
+
a malonyl-[acyl-carrier protein]
=
an acetoacetyl-[acyl-carrier protein]
+
CoA
+
CO2

Synonyms

3-ketoacyl ACP synthase III, 3-ketoacyl acyl carrier protein synthase III, 3-ketoacyl carrier protein synthase III, 3-ketoacyl-(acyl carrier protein) synthase IIIA, 3-ketoacyl-(acyl carrier protein) synthase IIIB, 3-ketoacyl-ACP synthase III, 3-ketoacyl-acyl carrier protein synthase III, 3-ketoacyl-acyl-carrier protein synthase III, 3-oxoacyl-ACP synthase III, 3-oxoacyl-acyl carrier protein synthase III, 3-oxoacyl-[acyl-carrier-protein] synthase III, 3-oxoacyl:ACP synthase III, AbyA1, acetoacetyl-ACP synthase, acetyl-CoA:ACP transacylase, acetyl-CoA:malonyl-[acyl-carrier-protein] C-acyltransferase, ACO synthase III, ACP synthase III, AknE2, AlnI, AsuC3, AsuC4, AviN, BenQ, beta-ketoacyl (acyl carrier protein) synthase III, beta-ketoacyl acyl carrier protein synthase III, beta-ketoacyl acyl-carrier protein synthase III, beta-ketoacyl-(ACP) synthase III, beta-ketoacyl-(acyl-carrier-protein) synthase III, beta-ketoacyl-ACP III, beta-ketoacyl-ACP synthase, beta-ketoacyl-ACP synthase III, beta-ketoacyl-ACP synthase III-like protein, beta-ketoacyl-ACP-synthase III, beta-ketoacyl-acyl carrier protein (ACP) synthase III, beta-ketoacyl-acyl carrier protein synthase III, beta-ketoacyl-acyl carrier protein synthase-III, beta-ketoacyl-[acyl-carrier protein (ACP)] synthase III, beta-ketoacyl-[acyl-carrier-protein] synthase III, beta-ketoacyl:acyl carrier protein synthase III, beta-ketoacylacylcarrier protein synthase III, beta-ketobutyryl-ACP synthase, BomK, CalO4, CerJ, ChlB3, ChlB6, CorB, DarB, DpsC, ecFabH, ecKAS III, efFabH, EsmD1, EvrI, FabH, FabH1, FabH2, FabH3, FabHA, FabHB, fatty acid biosynthesis, enzyme H, fatty acid synthase type II condensing enzyme, FdmS, FrenI/FrnI, HedS, hiFabH, initiation ketosynthase, JcKAS III, KAS III, KAS III-like protein, KAS IIIA, KAS IIIB, KAS-III, KAS3a, KAS3b, KASIII, KijB, LstA, LstAB, LstB, mtFabH, MxnB, nmFabH, NphT7, NzsF, paFabH, PpyS, PqsBC, PqsD, PtmR, RedP, RevR, RkD, saFabH, SalQ/Orf12, short-chain condensing enzyme, spFabH, spyFabH, SsfN, TcsB, ThgI, TiaF, Tmn15, [acyl-carrier-protein] synthase III

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.180 beta-ketoacyl-[acyl-carrier-protein] synthase III

IC50 Value

IC50 Value on EC 2.3.1.180 - beta-ketoacyl-[acyl-carrier-protein] synthase III

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.08
(5R)-4-hydroxy-3,5-dimethyl-5-tetradecylthiophen-2(5H)-one
Mycobacterium tuberculosis
-
-
0.08
(5R)-4-hydroxy-3,5-dimethyl-5-tridecylthiophen-2(5H)-one
Mycobacterium tuberculosis
-
-
0.017 - 0.019
(5R)-4-hydroxy-5-[[4'-(hydroxymethyl)biphenyl-4-yl]methyl]-3,5-dimethylthiophen-2(5H)-one
0.04
(5R)-5-dodecyl-4-hydroxy-3,5-dimethylthiophen-2(5H)-one
Mycobacterium tuberculosis
-
-
0.00702
(5R)-5-[3-(4-acetyl-3-hydroxyphenyl)prop-2-yn-1-yl]-4-hydroxy-3,5-dimethylthiophen-2(5H)-one
Mycobacterium tuberculosis
-
-
0.00404
(5R)-5-[3-(4-acetylphenyl)prop-2-yn-1-yl]-4-hydroxy-3,5-dimethylthiophen-2(5H)-one
Mycobacterium tuberculosis
-
-
1
(9E)-N-[(4-aminophenyl)sulfonyl]undec-9-enamide
Plasmodium falciparum
-
above
0.0094
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(2,4-dichlorophenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0401
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(2-bromophenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0275
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(3-bromophenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0082
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(3-fluorophenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0067
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(4-(benzyloxy)phenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0198
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(4-(dimethylamino)phenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0156
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(4-bromophenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0343
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(4-chlorophenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0025
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(biphenyl-4-yl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0489
(E)-1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl 3-(naphthalen-1-yl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0067
(E)-1-(6-chloropyridin-3-yl)-N-((3,4-dihydro-2Hbenzo[b][1,4]dioxepin-7-yl)methylene)methanamine
Escherichia coli
at pH 7.0 and 37°C
0.4477
(E)-2-(2,6-dimethylphenyl)ethenyl phenyl sulfone
Plasmodium falciparum
-
-
0.0123
(E)-4-chloro-N-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)methylene)pyridin-2-amine
Escherichia coli
at pH 7.0 and 37°C
0.0128
(E)-5-chloro-N-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)methylene)pyridin-2-amine
Escherichia coli
at pH 7.0 and 37°C
0.0099
(E)-6-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-methyleneamino)nicotinonitrile
Escherichia coli
at pH 7.0 and 37°C
0.043
(E)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-bromophenylamino)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0085
(E)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-isopropylphenylamino)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0857
(E)-N'-((E)-3-phenylallylidene)-2,3-dihydrobenzo[b][1,4]-dioxine-2-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.0074
(E)-N-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-methylene)-3-methylpyridin-2-amine
Escherichia coli
at pH 7.0 and 37°C
0.0151
(E)-N-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-methylene)-4-methylpyridin-2-amine
Escherichia coli
at pH 7.0 and 37°C
0.0038
(E)-N-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-methylene)-5-(trifluoromethyl)pyridin-2-amine
Escherichia coli
at pH 7.0 and 37°C
0.0145
(E)-N-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-methylene)pyridin-3-amine
Escherichia coli
at pH 7.0 and 37°C
0.0021
(E)-tert-butyl 4-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)methyleneamino)piperidine-1-carboxylate
Escherichia coli
at pH 7.0 and 37°C
0.1646
(Z)-1-methyl-2-phenylethenyl phenyl sulfone
Plasmodium falciparum
-
-
0.024
(Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(2,4-dibromophenylamino)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.028
(Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(2-chlorophenylamino)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0033
(Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-bromophenylamino)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0082
(Z)-ethyl 2-(4-(benzyloxy)phenyl)-3-(4-fluorophenylamino)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0026
(Z)-ethyl 3-(p-toluidino)-2-(4-(benzyloxy)phenyl)acrylate
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.00013
1,1'-disulfanediyldinaphthalen-2-ol
Plasmodium falciparum
-
-
0.006 - 0.026
1-(2,6-dichlorobenzyl)-5-[(3-methoxybenzyl)oxy]-1H-indole-2-carboxylic acid
0.015
1-(2,6-dichlorobenzyl)-5-[[2-fluoro-6-(trifluoromethyl)benzyl]oxy]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.004
1-(2,6-dichlorobenzyl)-5-[[4-(trifluoromethyl)benzyl]oxy]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.017
1-(2-bromobenzyl)-5-[(3-methoxybenzyl)oxy]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.0515
1-(2-chlorophenyl)-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylurea
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0025
1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-yl (2E)-3-(biphenyl-4-yl)prop-2-enoate
Escherichia coli
pH and temperature not specified in the publication
0.0717
1-(3,5-dibromo-2-hydroxybenzyl)-1-(4-fluorophenyl)-3-phenylurea
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.04
1-(4-carboxybenzyl)-5-[[2-fluoro-6-(trifluoromethyl)benzyl]oxy]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.00014 - 0.007
1-(4-carboxybutyl)-5-[(2,6-dichlorobenzyl)oxy]-1H-indole-2-carboxylic acid
0.0101
1-(4-chlorophenyl)-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylurea
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0043
1-(4-[(E)-[3-(benzyloxy)benzylidene]amino]phenyl)-3-phenylthiourea
Escherichia coli
pH and temperature not specified in the publication
0.0564
1-(5-bromo-2-hydroxybenzyl)-1-(2-bromophenyl)-3-phenylurea
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0218
1-(5-bromo-2-hydroxybenzyl)-1-(2-chlorophenyl)-3-phenylurea
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0374
1-(5-bromo-2-hydroxybenzyl)-1-(2-fluorophenyl)-3-phenylurea
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.041
1-(5-bromo-2-hydroxybenzyl)-1-(4-bromophenyl)-3-phenylurea
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0047
1-(5-bromo-2-hydroxybenzyl)-1-(4-chlorophenyl)-3-phenylurea
0.0066
1-(5-bromo-2-hydroxybenzyl)-1-(4-fluorophenyl)-3-phenylurea
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.042
1-(5-carboxypentyl)-5-[[2-fluoro-6-(trifluoromethyl)benzyl]oxy]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.0258
1-phenylethyl (2Z)-3-[(4,5-dimethyl-2-oxido-1,3,2-dioxaphospholan-2-yl)oxy]but-2-enoate
Plasmodium falciparum
-
-
0.00004 - 0.00088
1-[(6-chloro-1,3-benzodioxol-5-yl)methyl]-5-[(2,6-dichlorobenzyl)oxy]-1H-indole-2-carboxylic acid
0.0196
1-[3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
Escherichia coli
-
pH not specified in the publication, temperature not specified in the publication
0.0173
1-[3-(4-methoxyphenyl)-5-(4-methylphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
Escherichia coli
-
pH not specified in the publication, temperature not specified in the publication
0.0467
1-[3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethanone
Escherichia coli
-
pH not specified in the publication, temperature not specified in the publication
0.007 - 0.036
1-[4-(trifluoromethyl)benzyl]-5-[[4-(trifluoromethyl)benzyl]oxy]-1H-indole-2-carboxylic acid
0.0314
1-[5-(2-chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
Escherichia coli
-
pH not specified in the publication, temperature not specified in the publication
0.0104
1-[5-(4-bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
Escherichia coli
-
pH not specified in the publication, temperature not specified in the publication
0.0076
1-[5-(4-chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
Escherichia coli
-
pH not specified in the publication, temperature not specified in the publication
0.0042
1-[5-(4-fluorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
0.0382
2,2'-(benzene-1,3-diyldisulfonyl)dibenzene-1,4-diol
Plasmodium falciparum
-
-
0.00014
2,2'-disulfanediylbis(4-chlorophenol)
Plasmodium falciparum
-
-
0.0019
2,2'-disulfanediyldiphenol
Plasmodium falciparum
-
-
0.0031
2,2'-sulfanediylbis(4-chlorophenol)
Plasmodium falciparum
-
-
0.00053
2,2'-trisulfane-1,3-diylbis(4-chlorophenol)
Plasmodium falciparum
-
-
0.0036
2,4-dibromo-6-[(E)-[2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]methyl]phenol
Escherichia coli
pH and temperature not specified in the publication
0.0036
2,4-dibromo-6-[(E)-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazono]methyl]phenol
Escherichia coli
-
-
0.0784
2,4-dibromo-6-[(E)-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazono]methyl]phenol
Escherichia coli
-
-
0.0165
2,4-dichloro-6-[(E)-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazono]methyl]phenol
Escherichia coli
-
-
0.0576
2,4-dichloro-6-[(E)-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazono]methyl]phenol
Escherichia coli
-
-
0.00028
2,5-dichloro-4-nitro-N-[4-(trifluoromethyl)phenyl]thiophene-3-sulfonamide
Plasmodium falciparum
-
-
0.0022
2,5-dichloro-N-[4-(trifluoromethyl)phenyl]thiophene-3-sulfonamide
Plasmodium falciparum
-
-
0.0051
2-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-5-(2-methylbenzyl)-1,3,4-oxadiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0405
2-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-5-(4-nitrophenyl)-1,3,4-oxadiazol
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0016
2-((4-bromo-3-[(diethylamino)sulfonyl]benzoyl)amino)benzoic acid
Enterococcus faecalis
pH and temperature not specified in the publication
0.0043
2-(2-methoxyphenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0043
2-(2-methoxyphenyl)-5-[(2-methyl-5-nitro-1H-imidazol-1-yl)methyl]-1,3,4-oxadiazole
Escherichia coli
pH and temperature not specified in the publication
0.0169
2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0269
2-(3-bromophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0098
2-(3-bromophenyl)-N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0123
2-(3-chlorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0084
2-(3-diethylsulfamoyl-4-fluorobenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0084 mM
0.0114
2-(3-diethylsulfamoyl-4-methoxybenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0114 mM
0.0061
2-(3-diethylsulfamoyl-4-phenoxybenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0061 mM
0.0022
2-(3-diethylsulfamoyl-4-piperidin-1-ylbenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0022 mM
0.0094
2-(3-methoxyphenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.185
2-(3-phenoxy-4-piperazin-1-ylbenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.185 mM
0.00029
2-(3-phenoxy-4-piperidin-1-ylbenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.00029 mM
0.00011
2-(3-phenoxy-4-pyridin-3-ylbenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.00011 mM
0.0012
2-(3-phenoxy-4-thiomorpholin-4-ylbenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0012 mM
0.0027
2-(3-phenoxybenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0027 mM
1
2-(3-phenoxybenzoylamino)nicotinic acid
Enterococcus faecalis
-
IC50 is above 1.0 mM
0.043
2-(3-phenoxybenzoylamino)thiophene-3-carboxylic acid
Enterococcus faecalis
-
IC50 is 0.043 mM
0.16
2-(4-bromo-3-diethylsulfamoyl-5-methylbenzoylamino)-benzoic acid
Enterococcus faecalis
-
IC50 is 0.16 mM
0.0016
2-(4-bromo-3-diethylsulfamoylbenzoylamino)-benzoic acid
Enterococcus faecalis
-
IC50 is 0.0016 mM
0.000062
2-(4-bromo-3-phenoxybenzoylamino)-6-hydroxybenzoic acid
Enterococcus faecalis
-
IC50 is 0.000062 mM
0.0011
2-(4-bromo-3-phenoxybenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0011 mM
0.0438
2-(4-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0481
2-(4-bromophenyl)-N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0000088 - 0.0001287
2-(4-chlorobenzene-1-sulfonyl)naphthalene-1,4-diol
0.0283
2-(4-chlorophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0418
2-(4-chlorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0021
2-(4-cyclopentylmethoxy-3-diethylsulfamoylbenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0021 mM
0.0038
2-(4-fluoro-3-phenoxybenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0038 mM
0.0186
2-(4-fluorophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0384
2-(4-fluorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0001124 - 0.0003411
2-(4-methylbenzene-1-sulfonyl)anthracene-1,4-diol
0.0000136 - 0.0000736
2-(4-methylbenzene-1-sulfonyl)naphthalene-1,4-diol
0.0001872
2-(4-methylbenzene-1-sulfonyl)naphthalene-1,4-dione
Escherichia coli
pH 7.4, 23°C
0.0032
2-(4-morpholin-4-yl-3-phenoxybenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.0032 mM
0.0000097 - 0.0000726
2-(4-propylbenzene-1-sulfonyl)naphthalene-1,4-diol
0.00000212 - 0.0002787
2-(benzenesulfonyl)naphthalene-1,4-diol
0.00032
2-(butylsulfonyl)ethyl 4-nitrobenzoate
Plasmodium falciparum
-
-
0.0000275 - 0.0000873
2-(methanesulfonyl)naphthalene-1,4-diol
0.0000154 - 0.000393
2-(naphthalene-2-sulfonyl)naphthalene-1,4-diol
0.0629
2-(tert-butylsulfonyl)-1-(2,4-dichlorophenyl)ethanone
Plasmodium falciparum
-
-
0.0057
2-([[4-(3,5-dimethylpiperidin-1-yl)-3-phenoxyphenyl]carbonyl]amino)benzoic acid
Escherichia coli
-
-
0.0183
2-amino-6-(naphthalen-2-ylsulfonyl)quinazolin-4-ol
Plasmodium falciparum
-
-
0.0028
2-chloro-4-sulfanylphenol
Plasmodium falciparum
-
-
0.006
2-fluoro-6-(3-phenoxybenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.006 mM
0.005
2-hydroxy-4-[(phenylsulfonyl)amino]benzoic acid
Plasmodium falciparum
-
-
0.00041
2-hydroxy-6-(3-phenoxybenzoylamino)benzoic acid
Enterococcus faecalis
-
IC50 is 0.00041 mM
0.000004
2-hydroxy-6-[(2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.000004 mM
0.000004 - 0.0038
2-hydroxy-6-[[(2-phenoxybiphenyl-4-yl)carbonyl]amino]benzoic acid
0.00016
2-[(2',4'-difluoro-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00016 mM
0.0016
2-[(2-diethylsulfamoyl-biphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.0016 mM
0.00047
2-[(2-phenoxy-3'-trifluoromethoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00047 mM
0.000096
2-[(2-phenoxy-4'-trifluoromethylbiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.000096 mM
0.000056
2-[(2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.000056 mM
0.00033
2-[(3',4'-difluoro-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00033 mM
0.00057
2-[(3'-chloro-4'-fluoro-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00057 mM
0.00079
2-[(3'-isopropyl-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00079 mM
0.00025
2-[(4'-chloro-3'-methyl-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00025 mM
0.00022
2-[(4'-ethoxy-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00022 mM
0.00024
2-[(4'-fluoro-3'-methyl-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00024 mM
0.00041
2-[(4'-hydroxy-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00041 mM
0.000028
2-[(4'-methanesulfonyl-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.000028 mM
0.00016
2-[(4'-methyl-2-phenoxybiphenyl-4-carbonyl)amino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00016 mM
0.00044
2-[(4-aminocyclohexyl)sulfonyl]naphthalene-1,4-diol
Plasmodium falciparum
-
-
0.0638
2-[(4-aminophenyl)sulfonyl]benzene-1,4-diol
Plasmodium falciparum
-
-
0.1926
2-[(4-methylphenyl)sulfonyl]benzene-1,4-diol
Plasmodium falciparum
-
-
0.00038
2-[(4-methylphenyl)sulfonyl]naphthalene-1,4-diol
Plasmodium falciparum
-
-
0.0046
2-[3-(3,4-dichlorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole
Escherichia coli
pH and temperature not specified in the publication
0.0037
2-[3-(3-carboxyphenoxy)benzoylamino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.0037 mM
0.0197
2-[3-(4-bromophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-4-(4-methoxyphenyl)-1,3-thiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0097
2-[3-(4-bromophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0271
2-[3-(4-bromophenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0233
2-[3-(4-bromophenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0044
2-[3-(4-carboxyphenoxy)benzoylamino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.0044 mM
0.005
2-[3-(4-fluorophenoxy)benzoylamino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.005 mM
0.0084
2-[3-(4-fluorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0223
2-[3-(4-fluorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0899
2-[3-(4-methoxyphenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0306
2-[3-(4-methoxyphenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0136
2-[3-(4-methylphenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0109
2-[3-(4-methylphenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.01
2-[3-(pyridin-4-yloxy)benzoylamino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.010 mM
0.022
2-[3-phenoxy-4-(1H-pyrazol-4-yl)benzoylamino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.022 mM
0.038
2-[4-(3,5-dimethylpiperazin-1-yl)-3-phenoxybenzoylamino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.038 mM
0.00027
2-[4-(3,5-dimethylpiperidin-1-yl)-3-phenoxybenzoylamino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.00027 mM
0.025
2-[4-(4-methylpiperazin-1-yl)-3-phenoxybenzoylamino]benzoic acid
Enterococcus faecalis
-
IC50 is 0.025 mM
0.0032
2-[4-[3-bromo-4-(hydroxymethyl)phenyl]piperazin-1-yl]-1-(5-nitrofuran-2-yl)ethanone
Plasmodium falciparum
-
-
0.0184
2-[5-(furan-2-yl)-3-(4-methylphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0157
2-[5-(furan-2-yl)-3-(4-methylphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-4-(4-methoxyphenyl)-1,3-thiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0046
2-[5-(furan-2-yl)-3-(4-methylphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.002
2-[[(3-phenoxy-4-piperidin-1-ylphenyl)carbonyl]amino]benzoic acid
Escherichia coli
-
-
0.001
2-[[(3-phenoxy-4-thiomorpholin-4-ylphenyl)carbonyl]amino]benzoic acid
Escherichia coli
-
-
0.0000465 - 0.0000965
3-(1,4-dihydroxynaphthalene-2-sulfonyl)propanoic acid
0.0019 - 0.0216
3-(2-phenylethyl)-1,3-thiazolidin-2-one 1,1-dioxide
0.0555 - 0.1
3-(2-phenylethyl)-1,3-thiazolidine-2-thione
0.0019
3-(2-phenylethyl)-1lambda6,3-thiazolidine-1,1,2-trione
Escherichia coli
pH not specified in the publication, temperature not specified in the publication
0.29
3-(3-phenoxybenzoylamino)pyridine-2-carboxylic acid
Enterococcus faecalis
-
IC50 is 0.290 mM
0.0101
3-(3-phenoxybenzoylamino)thiophene-2-carboxylic acid
Enterococcus faecalis
-
IC50 is 0.0101 mM
0.0109 - 0.0671
3-(4-phenoxybenzyl)-1,3-thiazolidin-2-one
0.0009 - 0.0494
3-(4-phenoxybenzyl)-1,3-thiazolidin-2-one 1,1-dioxide
0.0556
3-(4-phenoxybenzyl)-1,3-thiazolidine-2-thione
Plasmodium falciparum
-
-
0.0109 - 0.0671
3-(biphenyl-4-ylmethyl)-1,3-thiazolidin-2-one
0.0009 - 0.0494
3-(biphenyl-4-ylmethyl)-1,3-thiazolidin-2-one 1,1-dioxide
0.0053 - 0.1
3-(biphenyl-4-ylmethyl)-1,3-thiazolidine-2-thione
0.0207 - 0.0784
3-(pyridin-3-ylmethyl)-1,3-thiazolidin-2-one
0.0734 - 0.1
3-(pyridin-3-ylmethyl)-1,3-thiazolidine-2-thione
0.0137 - 0.0909
3-benzyl-1,3-thiazolidin-2-one
0.0011 - 0.0676
3-benzyl-1,3-thiazolidin-2-one 1,1-dioxide
0.0616 - 0.1
3-benzyl-1,3-thiazolidine-2-thione
0.0011
3-benzyl-1lambda6,3-thiazolidine-1,1,2-trione
Escherichia coli
pH not specified in the publication, temperature not specified in the publication
0.0269
3-bromo-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.0058
3-bromo-N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]benzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.0123
3-chloro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.1
3-methyl-1,3-thiazolidin-2-one 1,1-dioxide
0.1
3-methyl-1,3-thiazolidine-2-thione
0.1
3-propyl-1,3-thiazolidin-2-one 1,1-dioxide
0.1
3-propyl-1,3-thiazolidine-2-thione
0.0024 - 0.0108
3-[(4'-cyclopentylbiphenyl-4-yl)methyl]-1,3-thiazolidin-2-one 1,1-dioxide
0.0272
3-[(4-aminophenyl)sulfonyl]-5-methylbenzene-1,2-diol
Plasmodium falciparum
-
-
0.0109
3-[(4-phenoxyphenyl)methyl]-1,3-thiazolidin-2-one
Escherichia coli
pH not specified in the publication, temperature not specified in the publication
0.0009
3-[(4-phenoxyphenyl)methyl]-1lambda6,3-thiazolidine-1,1,2-trione
Escherichia coli
pH not specified in the publication, temperature not specified in the publication
0.0111 - 0.0144
3-[4-(4-cyclopentylphenoxy)benzyl]-1,3-thiazolidin-2-one
0.0024 - 0.0108
3-[4-(4-cyclopentylphenoxy)benzyl]-1,3-thiazolidin-2-one 1,1-dioxide
0.0053 - 0.0177
3-[4-(4-cyclopentylphenoxy)benzyl]-1,3-thiazolidine-2-thione
0.0144
3-[[4-(4-cyclopentylphenoxy)phenyl]methyl]-1,3-thiazolidin-2-one
Escherichia coli
pH not specified in the publication, temperature not specified in the publication
0.0177
3-[[4-(4-cyclopentylphenoxy)phenyl]methyl]-1,3-thiazolidine-2-thione
Escherichia coli
pH not specified in the publication, temperature not specified in the publication
0.0024
3-[[4-(4-cyclopentylphenoxy)phenyl]methyl]-1lambda6,3-thiazolidine-1,1,2-trione
Escherichia coli
pH not specified in the publication, temperature not specified in the publication
0.0021
4'-(2-carboxyphenylcarbamoyl)-2'-phenoxybiphenyl-4-carboxylic acid
Enterococcus faecalis
-
IC50 is 0.0021 mM
0.003
4'-[(3-hydroxy-2,4-dimethyl-5-oxo-2,5-dihydrothiophen-2-yl)methyl]biphenyl-4-carboxylic acid
Mycobacterium tuberculosis
-
0.00024
4,4'-disulfanediylbis(2,3,6-trichlorophenol)
Plasmodium falciparum
-
-
0.0108
4,4'-sulfanediyldibenzene-1,3-diol
Plasmodium falciparum
-
-
0.00013
4,4'-sulfonylbis(3-chloroaniline)
Plasmodium falciparum
-
-
0.00016 - 0.002
4,5-dichloro-1,2-dithiole-3-one
0.00225
4,5-dichloro-3H-1,2-dithiol-3-one
Staphylococcus aureus
-
-
0.00319
4,5-dichloro-3H-1,2-dithiole-3-thione
Staphylococcus aureus
-
-
0.0111 - 0.0144
4-(4-biphenyl-4-ylcyclohexyl)-1,3-thiazolidin-2-one
0.0053 - 0.0177
4-(4-biphenyl-4-ylcyclohexyl)-1,3-thiazolidine-2-thione
1
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
Plasmodium falciparum
-
above
0.0434
4-bromo-2-[(E)-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazono]methyl]phenol
Escherichia coli
-
-
0.0068
4-bromo-2-[(E)-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazono]methyl]phenol
Escherichia coli
-
-
0.0481
4-bromo-N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]benzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.1146
4-chloro-2-[(4-hydroxyphenyl)sulfonyl]phenol
Plasmodium falciparum
-
-
0.0396
4-chloro-2-[(E)-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazono]methyl]phenol
Escherichia coli
-
-
0.0117
4-chloro-2-[(E)-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazono]methyl]phenol
Escherichia coli
-
-
0.0418
4-chloro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.0027
4-fluoro-2-[(E)-[[2-(4-hydroxyphenyl)ethyl]imino]methyl]phenol
Escherichia coli
pH and temperature not specified in the publication
0.0384
4-fluoro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.0537
4-methylphenyl naphthalen-2-yl sulfone
Plasmodium falciparum
-
-
0.1575
4-methylphenyl phenyl sulfone
Plasmodium falciparum
-
-
0.00078
4-phenyl-5-phenylimino-[1,2,4]dithiazolidin-3-one
Staphylococcus aureus
-
CAS-No. 5338-82-9, IC50 is 0.00078 mM
0.0018
4-[(1Z)-N,2-bis(4-chlorophenyl)ethanimidoyl]benzene-1,3-diol
Escherichia coli
pH and temperature not specified in the publication
0.718
5-benzyl-2-(2-bromoacetamido)thiazole-4-carboxylic acid
Mycobacterium tuberculosis
-
0.00192
5-chloro-4-phenyl-3H-1,2-dithiol-3-one
Staphylococcus aureus
-
-
0.0019
5-chloro-4-phenyl-[1,2]-dithiol-3-one
Staphylococcus aureus
-
CAS-No. 2425-05-0, IC50 is 0.0019 mM
0.017
5-[(2,6-dichlorobenzyl)oxy]-1-(4-methoxybenzyl)-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.006
5-[(2,6-dichlorobenzyl)oxy]-1-[4-(trifluoromethyl)benzyl]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.017
5-[(2-bromobenzyl)oxy]-1-(4-methoxybenzyl)-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.002
5-[(2-bromobenzyl)oxy]-1-[4-(trifluoromethyl)benzyl]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.02
5-[(4-methoxybenzyl)oxy]-1-[4-(trifluoromethyl)benzyl]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.015
5-[[2-fluoro-6-(trifluoromethyl)benzyl]oxy]-1-[4-(trifluoromethyl)benzyl]-1H-indole-2-carboxylic acid
Francisella tularensis subsp. holarctica
pH 7.0, 37°C
0.022
5-[[4-(hydroxyamino)phenyl]sulfonyl]-1,3-thiazol-2-amine
Plasmodium falciparum
-
-
0.00024
6-amino-2-hydroxy-2,5-dimethylhexanamide
Plasmodium falciparum
-
-
0.00052
benzyl (E)-2-[(4-methylphenyl)sulfanyl]ethenyl sulfone
Plasmodium falciparum
-
-
0.00063
bis(4-chlorophenyl)trisulfane
Plasmodium falciparum
-
-
0.0014
bis(4-methylphenyl)trisulfane
Plasmodium falciparum
-
-
0.0225
bis[4-(1-methylethyl)phenyl] sulfone
Plasmodium falciparum
-
-
0.2
cerulenin
Streptococcus pneumoniae
the IC50 is 0.2 mM
0.0434
Cinnamic acid
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.0571
CoA methyldisulfide
Escherichia coli
pH 7.4, 23°C
0.004
decanoyl-CoA
Cuphea lanceolata
-
IC50 is 0.004 mM
0.00045
decanoyl-[acyl-carrier protein]
Cuphea lanceolata
-
reversible, noncompetitive inhibition versus malonyl-[acyl-carrier-protein] and uncompetitive versus acetyl-CoA, IC50 is 0.00045 mM
0.0012
decyl-CoA disulfide
Mycobacterium tuberculosis
-
-
0.00065
diphenyl sulfide
Plasmodium falciparum
-
-
0.0026
ethyl (2Z)-2-[4-(benzyloxy)phenyl]-3-[(4-methylphenyl)amino]prop-2-enoate
Escherichia coli
pH and temperature not specified in the publication
0.0049
ethyl 4-methylpyridine-3-carboxylate
Plasmodium falciparum
-
-
0.00243
methyl 2-(2-bromoacetamido)-5-(3-chlorophenyl) thiazole-4-carboxylate
Mycobacterium tuberculosis
-
0.0032
methyl 2-(2-bromoacetamido)-5-phenylthiazole-4-carboxylate
Mycobacterium tuberculosis
-
0.1598
methyl 5-benzyl-2-(2-bromoacetamido)thiazole-4-carboxylate
Mycobacterium tuberculosis
-
0.0571
methyl-CoA disulfide
Escherichia coli
-
-
0.1
N'-[(1E,2E)-3-(2-fluorophenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-5-carbohydrazide
Escherichia coli
above, pH 7.4, 37°C
0.0035
N'-[(1E,2E)-3-(2-nitrophenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-5-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.0147
N'-[(1E,2E)-3-(2-nitrophenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-6-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.0113
N'-[(1E,2E)-3-(4-bromophenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-5-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.0148
N'-[(1E,2E)-3-(4-bromophenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-6-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.0591
N'-[(1E,2E)-3-(4-methoxyphenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-5-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.0066
N'-[(1E,2E)-3-(4-methoxyphenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-6-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.009
N'-[(1E,2E)-3-(4-nitrophenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-2-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.0094
N'-[(1E,2E)-3-(4-nitrophenyl)prop-2-en-1-ylidene]-2,3-dihydro-1,4-benzodioxine-5-carbohydrazide
Escherichia coli
pH 7.4, 37°C
0.0021
N'-[(E)-(3,5-dichloro-2-hydroxyphenyl)methylidene]-4-hydroxy-3-methoxybenzohydrazide
Escherichia coli
pH and temperature not specified in the publication
0.00088
N-(3-(5-bromo-2-hydroxybenzylideneamino)propyl)-2-hydroxybenzamide
Escherichia coli
pH and temperature not specified in the publication
0.1952
N-(3-chlorophenyl)benzenesulfonamide
Plasmodium falciparum
-
-
0.0053
N-(4-(4-bromophenyl)thiazol-2-yl)-2-(3-chlorophenyl)acetamid
Escherichia coli
pH and temperature not specified in the publication
0.1
N-(4-phenyl-1,3-thiazol-2-yl)benzamide
Escherichia coli
above, pH 7.0, 37°C, recombinant His-tagged enzyme
0.0481
N-(4-[[4-(acetylamino)phenyl]sulfonyl]phenyl)-2-hydroxybenzamide
Plasmodium falciparum
-
-
0.0052
N-[3,5-bis(trifluoromethyl)phenyl]-4-[[3,5-bis(trifluoromethyl)phenyl]amino]-3-nitrocyclopenta-1,3-diene-1-sulfonamide
Plasmodium falciparum
-
-
0.0656
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-2-(3-methoxyphenyl)acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0347
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-2-(4-chlorophenyl)acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0293
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-2-(4-fluorophenyl)acetamide
Escherichia coli
pH and temperature not specified in the publication
0.0093
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-chlorobenzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.0066
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-3-methoxybenzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.0347
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-chlorobenzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.0293
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-fluorobenzamide
Escherichia coli
pH 7.0, 37°C, recombinant His-tagged enzyme
0.1
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]benzamide
Escherichia coli
above, pH 7.0, 37°C, recombinant His-tagged enzyme
0.0301
octyl-CoA disulfide
Mycobacterium tuberculosis
-
-
0.0049
penicillin G
Escherichia coli
pH 7.0, 37°C
0.0015
S-[2-(4-methoxyphenyl)-2-oxoethyl] benzenesulfonothioate
Plasmodium falciparum
-
-
0.000016
SB418011
Streptococcus pneumoniae
potent inhibition, the IC50 is 16 nM
0.0285
secnidazole
Escherichia coli
-
pH 7.0, temperature not specified in the publication
0.008 - 0.7
thiolactomycin
0.0000118 - 0.0000296
[4-(1,4-dihydroxynaphthalene-2-sulfonyl)phenyl]carbamic acid
additional information
additional information
Staphylococcus aureus
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IC50 for platencin is 0.00391 ng/ml
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