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2.3.1.194: acetoacetyl-CoA synthase

This is an abbreviated version!
For detailed information about acetoacetyl-CoA synthase, go to the full flat file.

Word Map on EC 2.3.1.194

Reaction

acetyl-CoA
+
malonyl-CoA
=
acetoacetyl-CoA
 +
CoA
 +
CO2

Synonyms

AACS, Acetoacetyl-CoA synthase, Acetoacetyl-CoA synthetase, acetoacetyl-coenzyme A synthase, acetoacetyl-coenzyme A synthesizing enzyme, More, NphT7, nphT7SCL, thiolase superfamily acetoacetyl-CoA synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.194 acetoacetyl-CoA synthase

Source Tissue

Source Tissue on EC 2.3.1.194 - acetoacetyl-CoA synthase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
high enzyme expression level
Manually annotated by BRENDA team
-
expression of AACS in the brains of mouse embryos is dramatically increased between E16.5 and E18.5
Manually annotated by BRENDA team
prenatal nicotine exposure leads to decreased expression and increased DNA methylation in the proximal promoter of acetoacetyl-CoA synthetase
Manually annotated by BRENDA team
-
mRNA levels and the expression of AACS are increased during neurite outgrowth
Manually annotated by BRENDA team
additional information
-
AACS expression analysis during development, overview
Manually annotated by BRENDA team