2.3.1.201: UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase
This is an abbreviated version!
For detailed information about UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase, go to the full flat file.
Reaction
Synonyms
PGN_0002, UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronic acid3-N-acetyltransferase, UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase, WbpD, WlbB
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General Information
General Information on EC 2.3.1.201 - UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase
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physiological function
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the enzyme is required for B-band O-antigen biosynthesis in Pseudomonas aeruginosa
physiological function
gene PGN_0002 is a wbpD homolog which is required for synthesis of UDP-ManNAc(3NAc)A. A PGN_0002-deficient mutant demonstrates an A-LPS biosynthesis deficiency, a pigmentless phenotype and reduced hemagglutination and gingipain activities on the cell surface compared with wild-type cells. PGN_0002 mutants are not immunoreactive to anti-A-LPS, and no HBP35 and Rgp diffuse bands are observed
physiological function
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gene PGN_0002 is a wbpD homolog which is required for synthesis of UDP-ManNAc(3NAc)A. A PGN_0002-deficient mutant demonstrates an A-LPS biosynthesis deficiency, a pigmentless phenotype and reduced hemagglutination and gingipain activities on the cell surface compared with wild-type cells. PGN_0002 mutants are not immunoreactive to anti-A-LPS, and no HBP35 and Rgp diffuse bands are observed
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