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2.3.1.22: 2-acylglycerol O-acyltransferase

This is an abbreviated version!
For detailed information about 2-acylglycerol O-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.22

Reaction

acyl-CoA
+
2-acylglycerol
=
CoA
+
diacylglycerol

Synonyms

acyl CoA:monoacylglycerol acyltransferase, acyl CoA:monoacylglycerol acyltransferase-2, acyl coenzyme A-monoglyceride acyltransferase, acyl coenzyme A:diacylglycerol acyltransferase, acyl-CoA:monoacylglycerol acyltransferase, acyl-CoA:monoacylglycerol transferase, acyl-coenzyme A:monoacylglycerol acyltransferase, acylglycerol palmitoyltransferase, DGAT, DGAT1/ARAT, diacylglycerol acyltransferase, GPAT4, LPGAT1, lysophosphatidylglycerol acyltransferase 1, MFAT, MGAT, MGAT1, Mgat2, MGAT3, MGOT1, MGOT2, MGOT3, MOGAT1, MOGAT2, MOGAT3, monoacylglycerol acyltransferase, monoacylglycerol acyltransferase-2, monoacylglycerol O-acyltransferase, monoacylglycerol O-acyltransferase 1, monoglyceride acyltransferase, More, multifunctional O-acyltransferase, OLE3, oleosin 3, palmitoyltransferase, acylglycerol, wax ester synthase/acyl coenzyme A:diacylglycerol acyltransferase, WS/DGAT, [acyl CoA]monoacylglycerol acyltransferase 2

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.22 2-acylglycerol O-acyltransferase

Activating Compound

Activating Compound on EC 2.3.1.22 - 2-acylglycerol O-acyltransferase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
bovine serum albumin
-
deoxycholate
-
stimulates enzyme from intestinal mucosa
oleic acid
-
stimulates below 0.015 mM
palmitic acid
-
0.02-0.05 mM, stimulates
phosphatidic acid
-
stimulates
phosphatidylcholine
-
stimulates
Phospholipid
-
phosphatidylcholine/phosphatidylserine at 0.025 mg/ml stimulates 80%
sn-1,2-dioleoylglycerol
sphingomyelin
sphingosine
-
0.0025-0.0075 mM, activates
Tween 20
-
maximal stimulation in presence of 1.4 mg/ml