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2.3.1.221: noranthrone synthase

This is an abbreviated version!
For detailed information about noranthrone synthase, go to the full flat file.

Word Map on EC 2.3.1.221

Reaction

7 malonyl-CoA +

hexanoyl-[acyl-carrier protein]
= 7 CoA +
norsolorinic acid anthrone
+
[acyl-carrier protein]
+ 7 CO2 + 2 H2O

Synonyms

norsolorinic acid anthrone synthase, norsolorinic acid anthrone-producing polyketide synthase, PksA, polyketide synthase A

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.221 noranthrone synthase

Crystallization

Crystallization on EC 2.3.1.221 - noranthrone synthase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
purified recombinant selenomethionine-labeled of PksA TE, sitting drop vapour diffusion method, 5 mg/ml protein in 20 mM Tris-HCl pH 7.5 containing 5% glycerol and 2 mM DTT is mixed with well solution containing 0.2 M ammonium acetate, 0.1 M sodium citrate pH 5.6, and 30% PEG 4000, 25°C, 2 days, X-ray diffraction structure determination and analysis, modeling