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2.3.1.227: GDP-perosamine N-acetyltransferase

This is an abbreviated version!
For detailed information about GDP-perosamine N-acetyltransferase, go to the full flat file.

Reaction

acetyl-CoA
+
GDP-4-amino-4,6-dideoxy-alpha-D-mannose
=
CoA
+
GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose

Synonyms

acetyl-CoA:GDP-D-perosamine N-acetyltransferase, PerB

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.227 GDP-perosamine N-acetyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.3.1.227 - GDP-perosamine N-acetyltransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + GDP-4-amino-4,6-dideoxy-alpha-D-mannose
CoA + GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose
show the reaction diagram
-
GDP-4-amino-4,6-dideoxy-alpha-D-mannose (i.e. GDP-alpha-D-perosamine) is a component of the four sugar repeated subunit of the O-antigen of Escherichia coli O157:H7. The enzyme is involved in the biosynthesis of the precursor molecule GDP-N-acetyl-D-perosamine
GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose i.e. GDP-N-acetyl-alpha-D-perosamine
-
?