2.3.1.23: 1-acylglycerophosphocholine O-acyltransferase

This is an abbreviated version!
For detailed information about 1-acylglycerophosphocholine O-acyltransferase, go to the full flat file.

Reaction

Synonyms

1-acyl-sn-glycero-3-phosphocholine acyltransferase, 1-acylglycerol-3-phosphate O-acyltransferase 8, 1-acylglycerophosphocholine acyltransferase, 1-AGP acyltransferase 8, 1-AGPAT 8, 1-AGPAT7, acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase, acyl coenzyme A-monoacylphosphatidylcholine acyltransferase, acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase, acyl-CoA:glycerophosphocholine acyltransferase, acyl-CoA:lysocardiolipin acyltransferase 1, acyl-CoA:lysophosphatidylcholine acyltransferase, acyl-CoA:lysophosphatidylethanolamine acyltransferase 2, acyl-CoA:lysophospholipid acyltransferase, acyltransferase, lysolecithin, AGPAT7, AGPAT8, Alcat1, ALE1, At1g78690, AtLPLAT2, AYTL1, AYTL2, AYTL3, CF3, CG18445, CsLPCAT, GPCAT, hPrdx6, Lclat1, LPAT, LPC acyltransferase, LPCAT, LPCAT1, LPCAT2, LPCAT3, LPCAT4, LPEAT2, LPG acyltransferase, LPGAT, LPGAT1, LPLAT, LPLAT5, lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1, LYCAT, lyso-PAF acetyltransferase, lyso-PC acyltransferase, lyso-PC acyltransferase 1, lyso-phosphatidylcholine acyltransferase 1, lysolecithin acyltransferase, lysoPC acyltransferase, lysophosphatide acyltransferase, lysophosphatidylcholine acyl transferase, lysophosphatidylcholine acyltransferase, lysophosphatidylcholine acyltransferase 1, lysophosphatidylcholine acyltransferase 3, lysophosphatidylcholine acyltransferase 4, lysophosphatidylethanolamine acyltransferase 2, lysophosphocholine acyltransferase 1, lysophosphocholine acyltransferase 2, lysophosphocholine acyltransferase 3, lysophosphocholine acyltransferase 4, lysophospholipid acyltransferase, lysophospholipid:acyl-CoA acyltransferase, mboa-6, MBOAT protein Nes, MBOAT5, membrane-bound O-acyltransferase 5, mLPEAT2, More, mPrdx6, N-acylphosphatidylethanolamine synthase, NAPE synthase, PCAT1, PCAT2, PGAT, rPrdx6, YALI0E16797g, yeast tafazzin, Ypr140wp

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.23 1-acylglycerophosphocholine O-acyltransferase

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Results	in table
25	Activating Compound
741	AA Sequence
2	Application
1	CAS Registry Number
38	Cloned(Commentary)
533	Disease/ Diagnostics
7	Expression
54	General Information
2	General Stability
9	IC50 Value
110	Inhibitors
8	kcat/KM [mM/s]
6	Ki Value [mM]
65	KM Value [mM]
105	Localization
2	Metals/Ions
16	Molecular Weight [Da]
66	Natural Substrates/ Products (Substrates)
194	Organism
14	Pathway
39	pH Optimum
7	pH Range
3	Posttranslational Modification
32	Protein Variants
27	Purification (Commentary)
3	Reaction
1	Reaction Type
125	Reference
247	Source Tissue
52	Specific Activity [micromol/min/mg]
8	Storage Stability
328	Substrates and Products (Substrate)
20	Subunits
216	Synonyms
1	Systematic Name
44	Temperature Optimum [°C]
2	Temperature Range [°C]
9	Temperature Stability [°C]
2	Turnover Number [1/s]

Application

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Application on EC 2.3.1.23 - 1-acylglycerophosphocholine O-acyltransferase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

medicine

Homo sapiens

Q6P1A2

LPCAT3 may have potential as a therapeutic target for diseases, including atherosclerosis, non-alcoholic steatohepatitis, and carcinoma

756737

pharmacology

Homo sapiens

Q6P1A2

the enzyme is a potential therapeutic targets for the regulation of immune and inflammatory disorders

736546