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2.3.1.23: 1-acylglycerophosphocholine O-acyltransferase

This is an abbreviated version!
For detailed information about 1-acylglycerophosphocholine O-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.23

Reaction

acyl-CoA
+
1-acyl-sn-glycero-3-phosphocholine
=
CoA
+
1,2-diacyl-sn-glycero-3-phosphocholine

Synonyms

1-acyl-sn-glycero-3-phosphocholine acyltransferase, 1-acylglycerol-3-phosphate O-acyltransferase 8, 1-acylglycerophosphocholine acyltransferase, 1-AGP acyltransferase 8, 1-AGPAT 8, 1-AGPAT7, acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase, acyl coenzyme A-monoacylphosphatidylcholine acyltransferase, acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase, acyl-CoA:glycerophosphocholine acyltransferase, acyl-CoA:lysocardiolipin acyltransferase 1, acyl-CoA:lysophosphatidylcholine acyltransferase, acyl-CoA:lysophosphatidylethanolamine acyltransferase 2, acyl-CoA:lysophospholipid acyltransferase, acyltransferase, lysolecithin, AGPAT7, AGPAT8, Alcat1, ALE1, At1g78690, AtLPLAT2, AYTL1, AYTL2, AYTL3, CF3, CG18445, CsLPCAT, GPCAT, hPrdx6, Lclat1, LPAT, LPC acyltransferase, LPCAT, LPCAT1, LPCAT2, LPCAT3, LPCAT4, LPEAT2, LPG acyltransferase, LPGAT, LPGAT1, LPLAT, LPLAT5, lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1, LYCAT, lyso-PAF acetyltransferase, lyso-PC acyltransferase, lyso-PC acyltransferase 1, lyso-phosphatidylcholine acyltransferase 1, lysolecithin acyltransferase, lysoPC acyltransferase, lysophosphatide acyltransferase, lysophosphatidylcholine acyl transferase, lysophosphatidylcholine acyltransferase, lysophosphatidylcholine acyltransferase 1, lysophosphatidylcholine acyltransferase 3, lysophosphatidylcholine acyltransferase 4, lysophosphatidylethanolamine acyltransferase 2, lysophosphocholine acyltransferase 1, lysophosphocholine acyltransferase 2, lysophosphocholine acyltransferase 3, lysophosphocholine acyltransferase 4, lysophospholipid acyltransferase, lysophospholipid:acyl-CoA acyltransferase, mboa-6, MBOAT protein Nes, MBOAT5, membrane-bound O-acyltransferase 5, mLPEAT2, More, mPrdx6, N-acylphosphatidylethanolamine synthase, NAPE synthase, PCAT1, PCAT2, PGAT, rPrdx6, YALI0E16797g, yeast tafazzin, Ypr140wp

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.23 1-acylglycerophosphocholine O-acyltransferase

Source Tissue

Source Tissue on EC 2.3.1.23 - 1-acylglycerophosphocholine O-acyltransferase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
high expression of both isoforms LCAT1 and LCAT2
Manually annotated by BRENDA team
by retrieving LPCAT3 expression pattern from Genevestigator
Manually annotated by BRENDA team
-
determined by RT-PCR analysis
Manually annotated by BRENDA team
a pluripotent embryonic murine mesenchymal cell line
Manually annotated by BRENDA team
-
Ehrlich ascites
Manually annotated by BRENDA team
LPCAT4 mRNA expression is stronger in the hypertrophic than in the prehypertrophic zone of cartilage
Manually annotated by BRENDA team
-
endothelial cells
Manually annotated by BRENDA team
anterior and posterior
Manually annotated by BRENDA team
lysophosphatidylcholine acyltransferase 4 (LPCAT4) mRNA expression and LPCAT enzymatic activity towards oleoyl-, linoleoyl-, (5Z,8Z,11Z,14Z)-eicosatetraenoyl-, and docosahexaenoyl-CoA increases in the late stage of chondrogenic differentiation, when mineralization occurs
Manually annotated by BRENDA team
-
isolation of the microsomal fractions, three stages of seed development are chosen, 17, 24 and 31 days-after-flowering (DAF), in which it is possible to manually separate the embryo from the seed coat
Manually annotated by BRENDA team
-
priming of Mono-Mac-6 cells by IFNgamma appears to involve LPCAT
Manually annotated by BRENDA team
highly expressed, detected by Northern blot analysis
Manually annotated by BRENDA team
additional information